Waiting
登录处理中...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Neuroscience / Quantitative Analysis of Climbing Defects in a…
JoVE Journal
Neuroscience

需要订阅 JoVE 才能查看此 内容.

JoVE Journal Neuroscience
Quantitative Analysis of Climbing Defects in a Drosophila Model of Neurodegenerative Disorders
An Experimental Platform to Study the Closed-loop Performance of Brain-machine Interfaces
Journal (Neuroscience)
An Experimental Platform to Study the Closed-loop Performance of Brain-machine Interfaces
Subtype-selective Electroporation of Cortical Interneurons
Journal (Neuroscience)
Subtype-selective Electroporation of Cortical Interneurons
 

Quantitative Analysis of Climbing Defects in a Drosophila Model of Neurodegenerative Disorders

Article DOI: 10.3791/52741-v • 06:30 min • June 13th, 2015
June 13th, 2015 •
1, 1, 1, 1, 1, 1, 1, 2, 1
1Department of Pediatrics, University of Alberta, 2Montreal Neurological Institute and Hospital, McGill University

章节

总结概括
Automatic Translation

We present an optimized inexpensive and reliable negative geotaxis assay in Drosophila melanogaster as a model for neurodegenerative disorders. Being more sensitive to mild locomotor defects, this assay will help screen for potential genetic interactions and drug targets.

Tags

Quantitative Analysis Climbing Defects Drosophila Model Neurodegenerative Disorders Locomotive Defects Therapeutic Treatment Strategies Whole Exome Sequencing Genes Locomotive Functioning Reliable Assay Model Organisms Novel Targets Therapeutic Interest Negative Geotaxis Assay Glass Graduated Cylinder Wax Barrier Film Threshold Distance Experiment Duration Sensitivity Mild Mobility Dysfunctions Cost Effective Highly Reproducible Results Screening Candidate Drugs Drosophila Mutants
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter