Waiting
登录处理中...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Immunology and Infection / Humanized NOG Mice for Intravaginal HIV Exposure…
JoVE Journal
Immunology and Infection

需要订阅 JoVE 才能查看此 内容.

JoVE Journal Immunology and Infection
Humanized NOG Mice for Intravaginal HIV Exposure and Treatment of HIV Infection
Tractable Mammalian Cell Infections with Protozoan-primed Bacteria
Journal (Immunology and Infection)
Tractable Mammalian Cell Infections with Protozoan-primed Bacteria
Using Zebrafish Models of Human Influenza A Virus Infections to Screen Antiviral Drugs and Characterize Host Immune Cell Responses
Journal (Immunology and Infection)
Using Zebrafish Models of Human Influenza A Virus Infections to Screen Antiviral Drugs and Characterize Host Immune Cell Responses
 

Humanized NOG Mice for Intravaginal HIV Exposure and Treatment of HIV Infection

Article DOI: 10.3791/60723-v • 08:15 min • January 31st, 2020
January 31st, 2020 •
1,2, 1,2, 1,2, 1, 3, 1,4, 1,2, 1,2, 1,2,5, 1,2
1Department of Clinical Medicine, Aarhus University, 2Department of Infectious Diseases, Aarhus University Hospital, 3Department of Biomedicine, Aarhus University, 4Department of Gynecology and Obstetrics, Aarhus University Hospital, 5Department of Biology, University of Nebraska at Omaha

章节

总结概括
Automatic Translation

We have developed a protocol for the generation and evaluation of a humanized and human immunodeficiency virus-infected NOG mouse model based on stem cell transplant, intravaginal human immunodeficiency virus exposure, and droplet digital PCR RNA quantification.

Tags

Humanized NOG Mice Intravaginal HIV Exposure Treatment Of HIV Infection Preclinical HIV Research Viral Strains Novel HIV Interventions Stem Cell Donor CCR5 Variant Status Infect Humanized Mice With HIV Quantify Mouse Plasma Viral Loads RNA Quantification Protocol Viral RNA Sequence Genetic Screening CCR5 Delta 32 Variants PCR Mix High-fidelity DNA Polymerase Forward And Reverse Primers Agarose Gel Electrophoresis Intravaginal HIV Exposure Heating Lamp Sterile Pipette Tips
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter