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Journal / Cancer Research / En Murine Ommaya Xenograft-modell för att studera …
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JoVE Journal Cancer Research
En Murine Ommaya Xenograft-modell för att studera direktriktad terapi av leptomeningeal sjukdom
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En Murine Ommaya Xenograft-modell för att studera direktriktad terapi av leptomeningeal sjukdom

Article DOI: 10.3791/62033-v • 07:17 min • January 29th, 2021
January 29th, 2021 •
1,2, 3, 4, 4, 1, 5, 6, 7, 4, 2, 1,2
1Department of Neuro-Oncology, H. Lee Moffitt Cancer Center & Research Institute, 2Department of Tumor Biology, H. Lee Moffitt Cancer Center & Research Institute, 3Department of Comparative Medicine, University of South Florida, 4Department of Breast Oncology, H. Lee Moffitt Cancer Center & Research Institute, 5Department of Cancer Physiology, H. Lee Moffitt Cancer Center & Research Institute, 6Department of Drug Discovery, H. Lee Moffitt Cancer Center & Research Institute, 7Department of Medical Oncology, Roswell Park Comprehensive Cancer Center

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Här beskriver vi en murin xenograft modell som funktionellt liknar en Ommaya reservoar hos patienter. Vi utvecklade Murine Ommaya för att studera nya terapier för den universellt dödliga leptomeningeal sjukdomen.

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Cancerforskning Utgåva 167 Leptomeningeal sjukdom experimentella modeller murinmodell Murine Ommaya reservoar
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