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Anestesi och intubation av preadolescenta musungar för kardiotorakisk kirurgi
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Anestesi och intubation av preadolescenta musungar för kardiotorakisk kirurgi

Article DOI: 10.3791/64004-v • 09:47 min • June 2nd, 2022
June 2nd, 2022 •
*1, 1,2, 3,4, 1,2, 1,2, *1,2
1Molecular Cardiology and Biophysics Division, Victor Chang Cardiac Research Institute, 2St Vincent’s Clinical School, University of New South Wales Sydney, 3Department of Anaesthesia, The Children’s Hospital at Westmead, 4School of Child and Adolescent Health, University of Sydney
* These authors contributed equally

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Kardiotorakiska kirurgiska modeller hos möss >7 dagar gamla kräver intubation, men detta är utmanande för preadolescent (8-14 dagar gamla) musungar och det finns lite information om bedövningsregimer för intubation. Här presenterar vi doseringsregimer av ketamin / xylazin / atropin i 10 dagar gamla C57BL / 6J musungar som tillåter endotrakeal intubation, samtidigt som djurdödligheten minimeras.

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Biologi utgåva 184
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