Acupuncture Treatment in a Mouse Model of Chronic Hypoxia-Induced Cognitive Dysfunction

Fang Wan; Zhifang Guo; Mingye Wang; Yunlong Hou; Lu Wang; Wenyan Li; Ning Kang; Pengyu Zhu; Mengnan Li

doi:10.3791/65784

JoVE Journal
Behavior

A subscription to JoVE is required to view this content. Sign in or start your free trial.

JoVE Journal Behavior

Acupuncture Treatment in a Mouse Model of Chronic Hypoxia-Induced Cognitive Dysfunction

针灸治疗慢性缺氧诱导认知功能障碍小鼠模型

Full Text

1,829 Views

03:26 min

December 8, 2023

DOI: 10.3791/65784-v

Fang Wan*¹, Zhifang Guo*^2,3, Mingye Wang⁴, Yunlong Hou^5,6, Lu Wang^3,5, Wenyan Li^4,7, Ning Kang^2,3, Pengyu Zhu⁸, Mengnan Li^5,6

¹Heilongjiang University of Chinese Medicine, ²Hebei Provincial Key Laboratory of Luobing, ³Key Laboratory of State Administration of TCM (Cardio-Cerebral Vessel Collateral Disease), ⁴Hebei University of Chinese Medicine, ⁵Shijiazhuang Compound Traditional Chinese Medicine Technology Innovation Center, ⁶National Key Laboratory of Luobing Research and Innovative Chinese Medicine, ⁷Shijiazhuang Yiling Pharmaceutical Co., Ltd, ⁸The Second Affiliated Hospital of Heilongjiang University of Chinese Medicine

Please note that some of the translations on this page are AI generated. Click here for the English version.

在这里，我们描述了一种在慢性缺氧小鼠模型上实施轻度麻醉和针灸治疗的方案，并进行行为测试以评估治疗后的认知改变。

选择正确的麻醉方案对于进行小鼠针灸至关重要。由于与长时间麻醉相关的潜在认知障碍，它代表了一个重要的初始挑战，需要仔细考虑，以尽量减少手术过程中小鼠的认知功能风险。在这项研究中，我们提出了一种改进的方案，有助于最大限度地减少因过度麻醉剂量引起的功能和行为异常，并提高实验的准确性。

未来，我们的实验室旨在研究针灸的潜在机制，尽管它对行为和病理学有可观察到的治疗效果。我们的研究将集中在解开针灸上，以更深入地了解其机制。

View the full transcript and gain access to thousands of scientific videos

Explore More Videos

行为学第202期慢性缺氧认知障碍轻度麻醉非药物中药