Real-Time Detection of Ferulic Acid Effects on Rat Left Ventricle Using Pressure-Volume Conductivity Catheter

Zhihao Sun; Wenqiao An; Taiping He; Qingqing Liu; Ziming Wang; Pengmei Guo; Sanyin Zhang

doi:10.3791/65858

JoVE Journal
Medicine

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JoVE Journal Medicine

Real-Time Detection of Ferulic Acid Effects on Rat Left Ventricle Using Pressure-Volume Conductivity Catheter

使用压力-容积电导导管实时检测阿魏酸对大鼠左心室的影响

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04:27 min

January 12, 2024

DOI: 10.3791/65858-v

Zhihao Sun^1,2, Wenqiao An², Taiping He², Qingqing Liu², Ziming Wang², Pengmei Guo², Sanyin Zhang^2,3

¹School of Basic Medical Sciences,Chengdu University of Traditional Chinese Medicine, ²Innovative Institute of Chinese Medicine and Pharmacy,Chengdu University of Traditional Chinese Medicine, ³Research Institute of Integrated TCM & Western Medicine,Chengdu University of Traditional Chinese Medicine

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该协议描述了一种使用压力 - 体积电导技术测量左心室压力和体积的方法。这种方法可以连续实时监测药物对心脏的影响。

麻醉是动物实验中不可避免的问题。在本实验中，不同程度的麻醉对实验结果有显著影响。与开胸法相比，这种压力-容积环测量方法更易于学习，包括更少的实验工具和更少的实验人员学习时间。

我们的实验室将研究中医对心血管疾病的影响，探索其对心脏健康的广泛但尚未完全了解的影响。

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