Dual Extracellular Recordings in the Mouse Hippocampus and Prefrontal Cortex

Dechuan Sun; Mona Amiri; Luke Weston; Chris French

doi:10.3791/66003

JoVE Journal
Neuroscience

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JoVE Journal Neuroscience

Dual Extracellular Recordings in the Mouse Hippocampus and Prefrontal Cortex

小鼠海马体和前额叶皮层中的双重细胞外记录

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04:44 min

February 16, 2024

DOI: 10.3791/66003-v

Dechuan Sun^1,2, Mona Amiri¹, Luke Weston^1,2, Chris French¹

¹Neural Dynamics Laboratory, Department of Medicine,The University of Melbourne, ²Department of Electrical and Electronic Engineering,The University of Melbourne

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Summary

该协议概述了使用定制设计的记录设备和电极来记录局部场电位并研究小鼠海马体和前额叶皮层中的信息流。

Transcript

本研究提出了一种在小鼠海马体和前额叶皮层中执行双电极 LFP 记录的综合方案，以研究药物对这些区域的 LFP 特性的影响。该协议提供了一种低成本和超轻的脑信号记录设备，该设备针对小鼠的认知研究进行了全面优化。该研究提供了一种在不同脑区记录高信噪比信号的方法，有助于研究大脑内部的区域间信息通信。

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