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DOI: 10.3791/66038-v
Please note that some of the translations on this page are AI generated. Click here for the English version.
该手稿提出了使用超极化 Xenon-129 化学位移饱和恢复 (CSSR) 追踪肺气体交换、评估表观肺泡隔壁厚度并测量表面体积比的详细方案。该方法具有诊断和监测肺部疾病的潜力。
我们的研究重点是在 129 MRI 上使用超极化技术来评估肺功能和调查肺部疾病。主要目的是了解这种成像技术如何能够更好地检测、理解和跟踪不同的肺部疾病。大多数超极化肺部 MR 成像是在屏气期间进行的。
我们认为,在这种人工条件下量化的肺功能可能无法完全反映正常呼吸期间的气体交换,我们正在测试不需要任何屏气的新的自由呼吸测量值。目前的挑战包括优化 CSSR 采集技术,以确保在面对生理变化和患者依从性时的一致性和准确性。重症患者或儿科患者难以保持长时间的屏气。
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