Elia J. Duh Department of Ophthalmology, School of Medicine Johns Hopkins University Biography Publications Institution JoVE Articles Elia J. Duh has not added a biography. If you are Elia J. Duh and would like to personalize this page please email our Author Liaison for assistance. Publications Engineered Human Vascularized Constructs Accelerate Diabetic Wound Healing Biomaterials. Jun, 2016 | Pubmed ID: 27328431 Monomethyl Fumarate Promotes Nrf2-dependent Neuroprotection in Retinal Ischemia-reperfusion Journal of Neuroinflammation. 2015 | Pubmed ID: 26689280 Nrf2 in Ischemic Neurons Promotes Retinal Vascular Regeneration Through Regulation of Semaphorin 6A Proceedings of the National Academy of Sciences of the United States of America. Dec, 2015 | Pubmed ID: 26621751 Deletion of Placental Growth Factor Prevents Diabetic Retinopathy and is Associated with Akt Activation and HIF1α-VEGF Pathway Inhibition. Diabetes 2015;64:200-212 Diabetes. Mar, 2015 | Pubmed ID: 25713201 Neuroprotective Role of Nrf2 for Retinal Ganglion Cells in Ischemia-reperfusion Journal of Neurochemistry. Apr, 2015 | Pubmed ID: 25683606 Pigment Epithelium-derived Factor Inhibits Retinal Microvascular Dysfunction Induced by 12/15-lipoxygenase-derived Eicosanoids Biochimica Et Biophysica Acta. Mar, 2015 | Pubmed ID: 25562624 Transcription Factor MEF2C Suppresses Endothelial Cell Inflammation Via Regulation of NF-κB and KLF2 Journal of Cellular Physiology. Jun, 2015 | Pubmed ID: 25474999 Deletion of Placental Growth Factor Prevents Diabetic Retinopathy and is Associated with Akt Activation and HIF1α-VEGF Pathway Inhibition Diabetes. Jan, 2015 | Pubmed ID: 25187372 Induction of Endothelial RAGE Expression in Pterygium Molecular Vision. 2014 | Pubmed ID: 25593504 NRF2 Plays a Protective Role in Diabetic Retinopathy in Mice Diabetologia. Jan, 2014 | Pubmed ID: 24186494 Nrf2 Acts Cell-autonomously in Endothelium to Regulate Tip Cell Formation and Vascular Branching Proceedings of the National Academy of Sciences of the United States of America. Oct, 2013 | Pubmed ID: 24062466 Hypoxic Retinal Muller Cells Promote Vascular Permeability by HIF-1-dependent Up-regulation of Angiopoietin-like 4 Proceedings of the National Academy of Sciences of the United States of America. Sep, 2013 | Pubmed ID: 23959876 A Novel Mechanism for Glucocorticoid-induced Tightening of Endothelial Barriers Investigative Ophthalmology & Visual Science. Jun, 2013 | Pubmed ID: 23759428 Nanoparticle Diffusion In, and Microrheology Of, the Bovine Vitreous Ex Vivo Journal of Controlled Release : Official Journal of the Controlled Release Society. Apr, 2013 | Pubmed ID: 23369761 Novel Targets Against Retinal Angiogenesis in Diabetic Retinopathy Current Diabetes Reports. Aug, 2012 | Pubmed ID: 22638940 MEF2C Ablation in Endothelial Cells Reduces Retinal Vessel Loss and Suppresses Pathologic Retinal Neovascularization in Oxygen-induced Retinopathy The American Journal of Pathology. Jun, 2012 | Pubmed ID: 22521302 Gene Delivery Nanoparticles Specific for Human Microvasculature and Macrovasculature Nanomedicine : Nanotechnology, Biology, and Medicine. Oct, 2012 | Pubmed ID: 22306159 Inhibition of Pathological Retinal Angiogenesis by the Integrin αvβ3 Antagonist Tetraiodothyroacetic Acid (tetrac) Experimental Eye Research. Jan, 2012 | Pubmed ID: 22123068 Sema3A [corrected] Resists Retinal Revascularization Blood. Jun, 2011 | Pubmed ID: 21636713 Nrf2 Has a Protective Role Against Neuronal and Capillary Degeneration in Retinal Ischemia-reperfusion Injury Free Radical Biology & Medicine. Jul, 2011 | Pubmed ID: 21545836 Pigment Epithelium-derived Factor Regulates Lipid Metabolism Via Adipose Triglyceride Lipase Diabetes. May, 2011 | Pubmed ID: 21464445 TNFalpha is Required for Late BRB Breakdown in Diabetic Retinopathy, and Its Inhibition Prevents Leukostasis and Protects Vessels and Neurons from Apoptosis Investigative Ophthalmology & Visual Science. Mar, 2011 | Pubmed ID: 21212173 Antipermeability Function of PEDF Involves Blockade of the MAP Kinase/GSK/beta-catenin Signaling Pathway and UPAR Expression Investigative Ophthalmology & Visual Science. Jun, 2010 | Pubmed ID: 20089873 Pigment Epithelium-derived Factor Contributes to Insulin Resistance in Obesity Cell Metabolism. Jul, 2009 | Pubmed ID: 19583952 Vascular Endothelial Growth Factor Induces MEF2C and MEF2-dependent Activity in Endothelial Cells Investigative Ophthalmology & Visual Science. Aug, 2008 | Pubmed ID: 18450586 Renaming the DSCR1/Adapt78 Gene Family As RCAN: Regulators of Calcineurin FASEB Journal : Official Publication of the Federation of American Societies for Experimental Biology. Oct, 2007 | Pubmed ID: 17595344 Tissue Factor Pathway Inhibitor-2 is Upregulated by Vascular Endothelial Growth Factor and Suppresses Growth Factor-induced Proliferation of Endothelial Cells Arteriosclerosis, Thrombosis, and Vascular Biology. Dec, 2006 | Pubmed ID: 17023682 Vascular Endothelial Growth Factor Upregulates Expression of ADAMTS1 in Endothelial Cells Through Protein Kinase C Signaling Investigative Ophthalmology & Visual Science. Sep, 2006 | Pubmed ID: 16936124 Use of Topical Human Amniotic Fluid in the Treatment of Acute Ocular Alkali Injuries in Mice American Journal of Ophthalmology. Aug, 2006 | Pubmed ID: 16876508 A System for Inducible Gene Expression in Retinal Ganglion Cells Investigative Ophthalmology & Visual Science. Aug, 2005 | Pubmed ID: 16043868 Upregulation of Placental Growth Factor by Vascular Endothelial Growth Factor Via a Post-transcriptional Mechanism FEBS Letters. Feb, 2005 | Pubmed ID: 15710418 Persistence of Fetal Vasculature in a Patient with Knobloch Syndrome: Potential Role for Endostatin in Fetal Vascular Remodeling of the Eye Ophthalmology. Oct, 2004 | Pubmed ID: 15465551 VEGF Selectively Induces Down Syndrome Critical Region 1 Gene Expression in Endothelial Cells: a Mechanism for Feedback Regulation of Angiogenesis? Biochemical and Biophysical Research Communications. Aug, 2004 | Pubmed ID: 15358155 Increased Expression of Iron-regulating Genes in Monkey and Human Glaucoma Investigative Ophthalmology & Visual Science. May, 2004 | Pubmed ID: 15111596 Vitreous Levels of Pigment Epithelium-derived Factor and Vascular Endothelial Growth Factor: Implications for Ocular Angiogenesis American Journal of Ophthalmology. Apr, 2004 | Pubmed ID: 15059706 Long-term Survival in a Patient with Uveal Melanoma and Liver Metastasis Archives of Ophthalmology (Chicago, Ill. : 1960). Feb, 2004 | Pubmed ID: 14769612 Retinal Neuroprotection Against Ischemic Injury Mediated by Intraocular Gene Transfer of Pigment Epithelium-derived Factor Investigative Ophthalmology & Visual Science. Oct, 2003 | Pubmed ID: 14507898 Periocular Gene Transfer of SFlt-1 Suppresses Ocular Neovascularization and Vascular Endothelial Growth Factor-induced Breakdown of the Blood-retinal Barrier Human Gene Therapy. Jan, 2003 | Pubmed ID: 12614564 Pigment Epithelium-derived Factor Suppresses Ischemia-induced Retinal Neovascularization and VEGF-induced Migration and Growth Investigative Ophthalmology & Visual Science. Mar, 2002 | Pubmed ID: 11867604 Inducible Expression of Vascular Endothelial Growth Factor in Adult Mice Causes Severe Proliferative Retinopathy and Retinal Detachment The American Journal of Pathology. Feb, 2002 | Pubmed ID: 11839592 A Mouse Model of Retinal Ischemia-Reperfusion Injury Through Elevation of Intraocular Pressure Matthew J. Hartsock1, Hongkwan Cho1, Lijuan Wu1, Wan-Ju Chen1, Junsong Gong1, Elia J. Duh1 1Department of Ophthalmology, School of Medicine, Johns Hopkins University JoVE 54065 Medizin
A Mouse Model of Retinal Ischemia-Reperfusion Injury Through Elevation of Intraocular Pressure Matthew J. Hartsock1, Hongkwan Cho1, Lijuan Wu1, Wan-Ju Chen1, Junsong Gong1, Elia J. Duh1 1Department of Ophthalmology, School of Medicine, Johns Hopkins University JoVE 54065 Medizin