Cell Surface Morphology
Cell Surface Morphology - Related Videos
08:49
Cell Surface Receptor Identification Using Genome-Scale CRISPR/Cas9 Genetic Screens
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Cited by 8 •
2020
This manuscript describes a genome-scale cell-based screening approach to identify extracellular receptor-ligand interactions.
08:59
Determination of Aggregate Surface Morphology at the Interfacial Transition Zone (ITZ)
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Cited by 9 •
2019
Hereby, we proposed a protocol to illustrate the effect of aggregate surface morphology on the ITZ microstructure. The SEM-BSE image were quantitatively analyzed to obtain ITZ's porosity gradient via digital image processing and a K-means clustering algorithm was further employed to establish a relationship between porosity gradient and surface roughness.
01:21
Cell-surface Signaling
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2019
Hormones—or any molecule that binds to a receptor, known as a ligand—that are lipid-insoluble (water-soluble) are not able to diffuse across the cell membrane. In order to be able to affect a cell without entering it, these hormones bind to receptors on the cell membrane. When a first messenger, a hormone, binds to a receptor, a signal cascade is set off, causing second messengers, proteins inside the cell, to become activated, resulting in downstream effects. Variety of Receptor Families
15:08
Probing and Mapping Electrode Surfaces in Solid Oxide Fuel Cells
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Cited by 4 •
2012
We present a unique platform for characterizing electrode surfaces in solid oxide fuel cells (SOFCs) that allows simultaneous performance of multiple characterization techniques (e.g. in situ Raman spectroscopy and scanning probe microscopy alongside electrochemical measurements). Complementary information from these analyses may help to advance toward a more profound understanding of electrode reaction and degradation mechanisms, providing insights into rational design of better materials for...
09:13
Cell-surface Biotinylation Assay
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2023
A cell can regulate the amount of particular proteins on its cell membrane through endocytosis, following which cell surface proteins are effectively sequestered in the cytoplasm. Once within a cell, these surface proteins can be either destroyed or “recycled” back to the membrane. The cell surface biotinylation assay provides researchers with a way to study these phenomena. The technique makes use of a derivative of the small molecule biotin, which can label surface proteins and then be...
FAQs
Surface features reflect the coordinated behavior of several structural systems rather than a single component. The plasma membrane forms the outer boundary, while the cortical cytoskeleton supports it, adhesion connects the cell with surrounding structures, and surface projections modify its external profile. Changes in any of these elements can alter visible shape or texture and influence cellular interactions.
Distinctive size, shape, texture, and structural features can provide clues about what type of cell is being examined and whether its state has changed. Because the surface responds to membrane organization, cytoskeletal support, adhesion, and projections, morphological differences may reflect altered cellular behavior. Comparing these features helps connect visible structure with underlying function.
Morphological changes can accompany processes that require cells to alter their organization or interactions. During migration, differentiation, or cell–cell communication, shifts in surface structure may reflect changes in how cells contact their environment or one another. Examining these features therefore gives researchers a way to relate cellular appearance to broader biological processes without relying only on functional measurements.
A typical assessment combines microscopy to visualize the cell boundary with image analysis to examine the recorded features. Researchers can evaluate characteristics such as size, shape, texture, and surface structures, then compare those measurements across cells or experimental conditions. This approach turns visible differences into analyzable information for studying cellular state and behavior.
Such comparisons can reveal surface differences associated with disease-related cellular states. Researchers may examine whether diseased cells show altered size, shape, texture, or structural features relative to healthy cells. These observations help identify morphology that correlates with cellular condition and support investigations into how disease changes cell structure and its relationship with cellular function.
Researchers can image cells before and after exposure to a drug or environmental condition, then compare their surface features using morphological assessment and image analysis. Changes in size, shape, texture, or surface structures may indicate that the treatment or condition affected cellular state. The resulting comparisons help evaluate structural responses alongside broader biological effects.