Heart Ventricles

Heart ventricles are the two lower chambers of the heart that receive blood from the atria and pump it into the pulmonary and systemic circulations, making them essential for maintaining blood flow through the body. During each cardiac cycle, electrical activation triggers ventricular muscle contraction; valves prevent backward flow, while the thicker left ventricular wall generates the higher pressure required to supply the body and the right ventricle pumps blood to the lungs. Studying ventricular structure and function helps explain circulation, cardiac development, and disorders such as ventricular failure, while supporting diagnostic assessment and treatments for heart disease.

Heart Ventricles - Related Videos

Research

JoVE Journal - Medicine
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Implantation of Total Artificial Heart in Congenital Heart Disease

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Cited by 40 •

2014

This is a case report of a patient with congenitally corrected transposition of the great arteries (CCTGA) who received a total artificial heart (TAH) as a bridge to heart transplant. The TAH was successfully implanted with modifications to accommodate the patient's congenitally malformed heart.

Research

JoVE Journal - Biology

Zebrafish Brain Ventricle Injection

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Cited by 72 •

2009

After neural tube formation, the neuroepithelium constricts and folds while the tube fills with embryonic cerebrospinal fluid (eCSF) to form the embryonic brain ventricles. We developed this ventricle injection technique to better visualize the fluid filled space in contrast to the neuroepithelial shape in a live embryo.

A Novel Ex vivo Culture Method for the Embryonic Mouse Heart

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Cited by 10 •

2013

Developmental studies in the mouse are hampered by the inaccessibility of the embryo during gestation. To promote the long-term culture of the embryonic heart at late stages of gestation, we developed a protocol in which the excised heart is cultured in a semi-solid, dilute Matrigel.

In Vitro Culture of Epicardial Cells From Mouse Embryonic Heart

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Cited by 11 •

2016

The epicardium is an essential source of multipotent cardiovascular progenitor cells and paracrine factors that are required for cardiovascular development and regeneration. We describe here a method to culture mouse embryonic epicardial cells.

Manual Drainage of the Zebrafish Embryonic Brain Ventricles

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Cited by 9 •

2012

We present a method to collect cerebrospinal fluid (CSF) and to create a system which lacks CSF within the embryonic zebrafish brain ventricular system. This allows for further examination of CSF composition and its requirement during embryonic brain development.

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