Mouse Behavior

Mouse behavior is the study of how mice act and respond to internal states, environmental conditions, sensory cues, and interactions with other animals. Behavior emerges through activity in the nervous system, which integrates signals such as odors, sounds, touch, and changes in surroundings to guide movement, feeding, exploration, communication, learning, and stress responses. Researchers analyze these patterns in controlled tests and naturalistic settings to understand brain function, genetics, development, and social behavior. Mouse behavior studies also provide important models for investigating neurological and psychiatric disorders, evaluating treatments, and linking biological mechanisms to measurable outcomes.

Mouse Behavior - Related Videos

Research

JoVE Journal - Biology

Olfactory Behavioral Testing in the Adult Mouse

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Cited by 68 •

2009

Fundamental, yet unique properties of the rodent olfactory system have led to its increasing study among biologists. A relatively simple assessment of its function is then also needed. Here we describe sensitive tests for the characterization of mouse olfactory sensitivity and preference.

Behavioral Assessment of the Aging Mouse Vestibular System

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Cited by 48 •

2014

Motor control and balance performance are known to deteriorate with age. This paper presents a number of standard noninvasive behavioral tests with the addition of a simple rotary stimulus to challenge the vestibular system and show changes in balance performance in a murine model of aging.

Inducing Depression-like Behavior in a Mouse via Immobilization Stress

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2025

This video demonstrates the method of inducing chronic stress in a mouse through repeated immobilization, leading to corticosterone release and reduced glutamate receptor activity in neurons, which results in depression-like behavior.

Research

JoVE Journal - Behavior
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Behavioral Phenotyping of Murine Disease Models with the Integrated Behavioral Station (INBEST)

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Cited by 4 •

2015

Prolonged and comprehensive monitoring of mice in a home-cage environment provides a deeper understanding of aberrant behavior in murine models of brain diseases. This paper describes the Integrated Behavioral Station (INBEST) as the key component of contemporary behavioral analysis.

The Treadmill Fatigue Test: A Simple, High-throughput Assay of Fatigue-like Behavior for the Mouse

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Cited by 93 •

2016

Fatigue is a common, undertreated and frequently poorly-understood symptom in many diseases and disorders. New preclinical assays of fatigue may help to improve current understanding and future treatment of fatigue. To that end, the current protocol provides a novel means of measuring fatigue-like behavior in the mouse.

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