Palatine Tonsils
Palatine Tonsils - Related Videos
08:09
Efficient Isolation Protocol for B and T Lymphocytes from Human Palatine Tonsils
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Cited by 11 •
2015
Palatine tonsils are a rich source of B and T lymphocytes. Here we provide an easy, efficient and rapid protocol to isolate B and T lymphocytes from human palatine tonsils. The method described has been specifically adapted for studies of the viral etiology of tonsil inflammation known as tonsillitis.
01:30
Tonsillitis I: Introduction
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2024
Tonsillitis is inflammation of the tonsils, which are two lymphoid tissue masses at the back of the throat. This condition can cause discomfort and irritation in the throat. Etiology Three primary contributing factors have been identified. • Viruses: Viral infections are the most common cause of tonsillitis. Common viruses responsible for tonsillitis include rhinovirus, influenza, parainfluenza, Epstein-Barr virus, and adenovirus. • Bacteria: The predominant bacterium responsible for...
01:26
Tonsillitis II: Management
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2024
This lesson will focus on the different treatment options for managing tonsillitis, which typically depend on the cause and severity. • Acute viral tonsillitis treatment usually involves outpatient supportive management, including analgesia (acetaminophen) and oral hydration, corticosteroids (dexamethasone), salt-water gargles, and rest. • Bacterial tonsillitis is typically treated with penicillin as the primary choice, although cephalosporins can also be effective. Antibiotic therapy with...
15:40
An Effective Manual Deboning Method To Prepare Intact Mouse Nasal Tissue With Preserved Anatomical Organization
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Cited by 34 •
2013
The mammalian nose is a multi-functional organ with intricate internal structures. The nasal cavity is lined with various epithelia such as olfactory, ...
11:14
Ex Vivo Infection of Human Lymphoid Tissue and Female Genital Mucosa with Human Immunodeficiency Virus 1 and Histoculture
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Cited by 29 •
2018
Infection of human tissues with human immunodeficiency virus (HIV) ex vivo provides a valuable 3D model of virus pathogenesis. Here, we describe a protocol to process and infect tissue specimens from human tonsils and female genital mucosae with HIV-1 and maintain them in culture at the liquid-air interface.
FAQs
The crypts create additional epithelial surface area within the tonsillar tissue. By increasing contact between the lining and inhaled or swallowed antigens, they support sampling of material entering through the respiratory and digestive routes. This arrangement makes the tonsils useful for studying how surface anatomy influences local immune surveillance.
Antigen-presenting cells and lymphocytes work together to initiate local immune responses in the tonsils. Antigen-presenting cells help expose immune cells to material encountered at the epithelial surface, while lymphocytes participate in the response that follows. Studying their organization clarifies how immune recognition begins at mucosal entry sites.
Their position provides access to material carried along both the respiratory and digestive tracts. This placement allows the tissue to encounter inhaled and swallowed antigens before those materials move deeper into the body. Consequently, palatine tonsils offer a model for examining how location influences early immune recognition.
Palatine tonsils connect surface exposure with organized lymphoid immune activity. Their crypt-containing epithelium, antigen-presenting cells, and lymphocytes show how a mucosal site can detect encountered antigens and support a local response. In biology, this makes them useful for examining the relationship between tissue structure, immune-cell organization, and antibody production.
Tonsillitis and tonsil hypertrophy are important conditions associated with palatine tonsils. Studying these conditions places their lymphoid organization and surface crypts in a clinically relevant context. It also allows researchers to consider how changes involving this tissue relate to immune activity and the function of a mucosal entry site.
Research can examine how palatine tonsils support the production of immune cells and antibodies after antigen exposure. These outcomes help investigators study recognition of potential pathogens at the tract entrances and consider how local responses may act before such agents spread deeper into the body. The tissue therefore links cellular organization with early protective function.