Stent Deployment

Stent deployment is a minimally invasive procedure that places a small mesh tube inside a narrowed or weakened blood vessel to maintain its diameter and improve blood flow. Guided by imaging, a catheter delivers the compressed stent to the target site, where balloon expansion or the stent’s self-expanding structure presses it against the vessel wall; drug-eluting coatings can reduce tissue regrowth that may cause restenosis. In biology and medical research, stent deployment provides a model for studying vascular injury, inflammation, endothelial healing, and blood-clot formation. The technique supports treatment of arterial disease while informing the design and evaluation of safer, more durable vascular implants.

Stent Deployment - Related Videos

Research

JoVE Journal - Bioengineering

Monitoring the Wall Mechanics During Stent Deployment in a Vessel

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2012

Stent-induced arterial strain distributions are characterized using an optical surface strain measurement system. This visualization technique is used to gain insights into the impact of stent implantation on the host vessel.

Fabrication of Small Caliber Stent-grafts Using Electrospinning and Balloon Expandable Bare Metal Stents

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Cited by 10 •

2016

In the protocol, we present a method to manufacture a small caliber stent-graft by sandwiching a balloon expandable stent between two electrospun nanofibrous polyurethane layers.

Research

JoVE Journal - Biology
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Imaging In-Stent Restenosis: An Inexpensive, Reliable, and Rapid Preclinical Model

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Cited by 5 •

2009

This video demonstrates how to use a preclinical inexpensive and reliable model to study pathobiological and pathophysiological processes of in-stent restenosis development. Longitudinal in vivo monitoring using OCT (Optical Coherence Tomography) and analysis of OCT images are also demonstrated.

Human Internal Mammary Artery (IMA) Transplantation and Stenting: A Human Model to Study the Development of In-Stent Restenosis

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Cited by 5 •

2012

This video shows a model to study the development of intimal hyperplasia after stent deployment using a human vessel (IMA) in an immunodeficient rat model.

Vascular Gene Transfer from Metallic Stent Surfaces Using Adenoviral Vectors Tethered through Hydrolysable Cross-linkers

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Cited by 12 •

2014

These studies report on reversible attachment of adenoviral gene vectors to coatless metal surfaces of stents and model mesh disks. Sustained release of transduction-competent viral particles contingent upon hydrolysis of cross-linkers used for vector immobilization results in a durable site-specific transgene expression in vascular cells and in stented arteries.

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