Ventral Laminectomy
Ventral Laminectomy - Related Videos
09:10
The Preparation of Oblique Spinal Cord Slices for Ventral Root Stimulation
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Cited by 1 •
2016
We show how to prepare oblique slices of the spinal cord in young mice. This preparation allows for the stimulation of the ventral roots.
05:13
Co-culturing of Ventral Hippocampal and Nucleus Accumbens
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2025
This video demonstrates the process of preparing ventral hippocampal and nucleus accumbens tissues from mouse brains for co-culture. Neurons extend projections to form synaptic connections between the ventral hippocampal and nucleus accumbens tissues. This method allows studying neuronal interactions between these two brain regions, offering insights into cognition, behavior, and neurological disorders.
10:49
Intraspinal Cell Transplantation for Targeting Cervical Ventral Horn in Amyotrophic Lateral Sclerosis and Traumatic Spinal Cord Injury
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Cited by 30 •
2011
Neural precursor transplantation is a promising strategy for protecting and/or replacing lost/dysfunctional cervical phrenic motor neurons in spinal cord injury (SCI) and the motor neuron disorder, amyotrophic laterals sclerosis (ALS). We provide a protocol for cell delivery to cervical spinal cord ventral horn in rodent models of ALS and SCI.
06:59
Laminectomy and Spinal Cord Window Implantation in the Mouse
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2019
This protocol describes implantation of a glass window onto the spinal cord of a mouse to facilitate visualization by intravital microscopy.
09:19
In ovo Expression of MicroRNA in Ventral Chick Midbrain
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Cited by 5 •
2013
Ectopic expression is one technique to elucidate the microRNAs role in brain development. However, targeting specific areas using in ovo electroporation is challenging. Here, we show an efficient way to selectively electroporate ventral and dorsal midbrain regions.
FAQs
Relieving pressure creates additional room around compressed neural tissue, which can reduce the mechanical obstruction affecting the spinal cord or nerve roots. This decompression may lessen neurological impairment and support functional recovery. The benefit depends on addressing the structure responsible for compression while avoiding damage to nearby neural tissue during removal.
The obstructing material may include bone, intervertebral disc material, or another space-occupying tissue. Removing the relevant compressive structure targets the source of pressure rather than simply enlarging the canal without a specific objective. At the same time, preserving spinal stability and neural structures is essential because decompression should improve available space without compromising the vertebral support system or nervous tissue.
A ventral route provides direct access to structures occupying the front-facing portion of the spinal canal. This orientation can allow clinicians to reach selected compressive bone, disc material, or lesions from the side closest to the obstruction. The approach therefore supports both decompression and, when appropriate, direct access for diagnosis or removal of a space-occupying lesion.
Clinicians may consider this procedure for selected cases of spinal cord compression associated with intervertebral disc disease, stenosis, or space-occupying lesions. The shared concern is reduced space around neural tissue, although the material causing compression can differ among conditions. Selection depends on whether the ventral approach can address the obstruction while maintaining spinal stability and protecting neural structures.
The procedure begins with ventral access to the spinal canal, followed by identification and excision of the bone or other tissue producing compression. Disc material or a space-occupying lesion may also be removed when it contributes to the obstruction. Throughout the intervention, clinicians aim to preserve neural structures and spinal stability while restoring room around the affected tissue.
Ventral laminectomy can provide direct access to an obstructing lesion, allowing clinicians to support diagnosis or remove the lesion when appropriate. Its principal therapeutic outcome is restoration of space around the spinal cord or nerve roots. By reducing compression, the procedure may lessen neurological impairment and create conditions that support functional recovery in selected cases.