Metathesis Reaction

A metathesis reaction is a chemical transformation in which two reactants exchange bonds or molecular partners to form new products, making it an important strategy for reorganizing chemical structures. In ionic double-displacement reactions, oppositely charged components exchange between compounds, often producing a precipitate, gas, or weak electrolyte that drives the reaction; in alkene metathesis, metal-carbene catalysts rearrange carbon-carbon double bonds through cycloaddition and cycloreversion steps. Chemists use metathesis to synthesize salts, polymers, pharmaceuticals, and specialized organic molecules. Its predictable bond reorganization and catalytic efficiency support cleaner, more selective synthesis in research and industrial chemistry.

Metathesis Reaction - Related Videos

Education

JoVE Core - Chemistry

Precipitation Reactions

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2020

In a precipitation reaction, aqueous solutions of soluble salts react to give an insoluble ionic compound – the precipitate. The reaction occurs when oppositely charged ions in solution overcome their attraction for water and bind to each other, forming a precipitate that separates out from the solution. Since such reactions involve the exchange of ions between ionic compounds in aqueous solution, they are also referred to as double displacement, double replacement, exchange reactions, or...

Olefin Metathesis Polymerization: Acyclic Diene Metathesis (ADMET)

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2023

Acyclic diene metathesis polymerization or ADMET polymerization involves cross-metathesis of terminal dienes, such as 1,8-nonadiene, to give linear unsaturated polymer and ethylene. As ADMET is a reversible process, the formed ethylene gas must be removed from the reaction mixture to complete the polymerization process. Similar to cross-metathesis, ADMET also involves the formation of metallacyclobutane intermediate by [2+2] cycloaddition of one of the double bonds of a terminal diene with...

Olefin Metathesis Polymerization: Ring-Opening Metathesis Polymerization (ROMP)

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2023

Ring-opening metathesis polymerization or ROMP involves strained cycloalkenes as starting materials. The mechanism of ROMP proceeds by reacting cycloalkene with Grubbs catalyst to give metallacyclobutane intermediate which undergoes a ring-opening reaction to form new carbene. The new carbene reacts with another molecule of cycloalkene. Repetition of these steps leads to the formation of an unsaturated open-chain polymer product. All these steps are reversible, however, relieving the ring...

Olefin Metathesis Polymerization: Overview

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2023

Recently, the development of olefin metathesis polymerization advanced the field of polymer synthesis. Simply put, the reorganization of substituents on their double bonds between two olefins in the presence of a catalyst is known as the olefin metathesis reaction. The use of metathesis reaction for polymer synthesis is called olefin metathesis polymerization. Ruthenium-based Grubbs catalyst is the most commonly used catalyst for olefin metathesis polymerization. Grubbs catalyst consists of a...

Research

JoVE Journal - Chemistry

Photogeneration of N-Heterocyclic Carbenes: Application in Photoinduced Ring-Opening Metathesis Polymerization

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Cited by 2 •

2018

We describe a protocol to photogenerate N-heterocyclic carbenes (NHCs) by UV irradiation of a 2-isopropylthioxanthone/imidazolium tetraphenylborate salt system. Methods to characterize the photoreleased NHC and elucidate the photochemical mechanism are proposed. The protocols for ring-opening metathesis photopolymerization in solution and miniemulsion illustrate the potential of this 2-component NHC photogenerating system.

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