Premature Ventricular Complexes
Premature Ventricular Complexes - Related Videos
04:12
Modeling Posthemorrhagic Hydrocephalus of Prematurity in Rats
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Cited by 3 •
2025
Posthemorrhagic hydrocephalus of prematurity (PHHP) can be modeled in neonatal rats by combining chorioamnionitis and intraventricular hemorrhage. The combination of these prenatal and postnatal events accurately recapitulates the clinical hallmarks of PHHP, including macrocephaly, ventriculomegaly, and elevated intracranial pressure, through the lifespan.
07:36
Modeling Encephalopathy of Prematurity Using Prenatal Hypoxia-ischemia with Intra-amniotic Lipopolysaccharide in Rats
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Cited by 20 •
2015
Encephalopathy of prematurity encompasses the central nervous system abnormalities associated with injury from preterm birth. This report describes a clinically relevant rat model of in utero transient systemic hypoxia-ischemia and intra-amniotic lipopolysaccharide administration (LPS) that mimics chorioamnionitis, and the related impact of infectious stimuli and placental underperfusion on CNS development.
08:49
Use of Two Intracorporeal Ventricular Assist Devices As a Total Artificial Heart
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Cited by 4 •
2018
Here, we present a protocol using two centrifugal pumps as a total artificial heart replacement.
09:22
Chronic Thromboembolic Pulmonary Hypertension and Assessment of Right Ventricular Function in the Piglet
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Cited by 22 •
2015
Chronic Thromboembolic Pulmonary Hypertension (CTEPH) and Right Ventricular (RV) dysfunction were induced in piglets by progressive obstruction of the pulmonary arteries. Consequences were remarkably similar to those observed in CTEPH patients. This animal model would be a very useful tool for pathophysiology and therapeutic experiments on CTEPH and RV failure.
11:33
Isolation and Kv Channel Recordings in Murine Atrial and Ventricular Cardiomyocytes
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Cited by 15 •
2013
Kv channel dysfunction is associated with cardiac arrhythmias. In order to study the molecular mechanisms that lead to such arrhythmias we utilize a systematic protocol for isolation of atrial and ventricular cardiomyocytes from Kv channel ancillary subunit knockout mice. Isolated cardiomyocytes can then immediately be used for cellular electrophysiological studies, biochemical or immunofluorescence (IF) assays.
FAQs
The timing of a PVC changes the expected electrical sequence: an ectopic ventricular focus depolarizes before the next sinus impulse, creating a wide, abnormal QRS complex. A pause may follow before the rhythm resumes. This sequence helps clinicians distinguish an early ventricular beat from the patient's underlying sinus rhythm on an electrocardiogram.
PVCs can appear as isolated events or occur frequently, and that pattern matters clinically. An occasional isolated beat may be observed in a person without structural heart disease, whereas a high burden raises the need for further assessment. Frequency therefore adds context beyond the appearance of any single abnormal QRS complex.
Palpitations can make PVCs clinically noticeable, but symptoms alone do not establish the underlying cause. PVCs may occur without structural heart disease, yet frequent beats or concerning symptoms can prompt evaluation for an underlying cardiac disorder. Clinical interpretation therefore combines the patient's experience with rhythm findings and assessment of cardiac structure.
Electrocardiography provides a direct snapshot of the abnormal beat and its timing within the rhythm. Clinicians can assess the QRS appearance, identify whether beats are isolated or frequent within the recording, and relate the finding to the surrounding sinus rhythm. This initial test helps determine whether additional monitoring or imaging is appropriate.
Ambulatory monitoring extends rhythm assessment beyond the brief ECG recording. It can capture PVCs over a longer period, helping characterize how often they occur and whether symptoms coincide with the abnormal beats. This information is especially useful when palpitations are intermittent or when a short clinical recording may not represent the person's usual rhythm.
Imaging contributes structural context that an electrical tracing alone cannot provide. In patients with PVCs, it helps clinicians evaluate whether an underlying cardiac disorder may be present, an important distinction because these beats can occur with or without structural heart disease. Combined with ECG and ambulatory data, imaging supports risk assessment and management decisions.