Prostate Anatomy
Prostate Anatomy - Related Videos
02:34
Individual Lobe Extraction from Prostate: A Technique to Harvest Individual Prostate Lobes from Mouse Prostate
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2023
This video describes a technique to harvest individual lobes from the prostate gland of a mouse model. Individual lobes can then be used for histological analysis and cancer research.
03:24
Extracting Prostate from Mouse Urogenital System: A Technique to Separate Prostate Gland from Other Urinary and Genital System Organs in Male Mouse
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2023
In this video, we describe the procedure for the dissection of the urogenital system or UGS from a male mouse model. This UGS is further dissected ex vivo to isolate the prostate gland and study its role in prostate cancer development.
08:38
Renal Capsule Xenografting and Subcutaneous Pellet Implantation for the Evaluation of Prostate Carcinogenesis and Benign Prostatic Hyperplasia
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Cited by 13 •
2013
We describe the manufacture of compressed hormone pellets, as well as subcutaneous surgical implantation into mice. This strategy can be combined with the growth of cell and tissue xenografts under the renal capsule of athymic nude mice to evaluate hormonal carcinogenesis and regulation of benign prostate growth.
08:49
Murine Prostate Micro-dissection and Surgical Castration
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Cited by 23 •
2016
This manuscript describes the protocols for prostate micro-dissection and surgical castration in the laboratory mouse. We also depict representative results produced by these protocols. Finally, we discuss the advantages and utilization of these protocols.
05:07
Intra-prostatic Injection of Cancer Cells: A Technique to Deliver Cancer Cells for Establishing Orthotopic Prostate Cancer Mouse Model
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2023
In this video, we demonstrate the procedure for administering intra-prostatic injection of prostate cancer cells into a mouse model. Orthotopic murine models can be used to study the disease origin and response to treatment therapies in a non-invasive and clinically relevant environment.
FAQs
Epithelial cells produce prostatic fluid, making the glandular tissue important to the composition of reproductive secretions. Smooth muscle provides a contractile component that helps propel those secretions into the urethra during ejaculation. This division of labor explains why prostate anatomy must be considered in relation to both tissue organization and the gland’s connection with the urethral passage.
Because the prostate surrounds the proximal urethra, changes in gland size or tissue organization can influence the space available for urinary flow. This anatomical relationship helps explain why clinical assessment of the prostate includes attention to urinary symptoms and why prostate findings can have consequences beyond the gland itself, particularly when neighboring structures are also affected.
Alterations in prostate size, tissue organization, or neighboring structures may influence two closely related functions. Changes near the urethra can affect urinary flow, while disruption of the gland’s secretory and contractile roles can affect sexual function. These relationships give clinicians an anatomical framework for interpreting symptoms associated with benign prostatic enlargement, prostatitis, and prostate cancer.
The same anatomical framework supports evaluation of several conditions, but each may be associated with different changes in gland size, tissue organization, or nearby structures. Benign prostatic enlargement, prostatitis, and prostate cancer therefore require clinical interpretation rather than relying on location alone. Understanding the normal arrangement provides a reference for recognizing and assessing these disease-related changes.
Imaging interpretation depends on recognizing the prostate’s position below the bladder, its relationship to the proximal urethra, and its connections with neighboring structures. Anatomical knowledge helps clinicians evaluate whether observed changes involve gland size, tissue organization, or surrounding relationships. This context makes imaging findings more useful when assessing suspected enlargement, prostatitis, or prostate cancer.
Biopsy and surgical planning require clinicians to account for the arrangement of glandular tissue, ducts, connective tissue, smooth muscle, and nearby structures. The prostate’s position and urethral relationship help frame how tissue changes may be sampled or managed. Anatomical understanding also supports planning that considers potential effects on urinary flow and sexual function.