Journal
/
Medicine
/
Renal Capsule Xenografting and Subcutaneous Pellet Implantation for the Evaluation of Prostate Carcinogenesis and Benign Prostatic Hyperplasia
JoVE Journal
Medicine
A subscription to JoVE is required to view this content.  Sign in or start your free trial.
JoVE Journal Medicine
Renal Capsule Xenografting and Subcutaneous Pellet Implantation for the Evaluation of Prostate Carcinogenesis and Benign Prostatic Hyperplasia

Renal Capsule Xenografting and Subcutaneous Pellet Implantation for the Evaluation of Prostate Carcinogenesis and Benign Prostatic Hyperplasia

DOI:
10.3791/50574-v

•

08:38 min

•

August 28, 2013

•

, , , , ,
1Department of Urology,University of Wisconsin-Madison, 2Medical Scientist (MD/PhD) Training Program,University of Rochester School of Medicine & Dentistry, 3Molecular and Environmental Toxicology Center,University of Wisconsin-Madison

Chapters

  • 00:05Title
  • 01:44Preparation of Compressed Hormone Pellet
  • 02:57Preparation of Fire Polished Glass Pipette
  • 03:27Renal Capsule Xenografting
  • 06:02Subcutaneous Pellet Implantation
  • 06:35Results: Renal Capsule Grafting
  • 07:17Conclusion

Summary

Automatic Translation

Automatic Translation

We describe the manufacture of compressed hormone pellets, as well as subcutaneous surgical implantation into mice. This strategy can be combined with the growth of cell and tissue xenografts under the renal capsule of athymic nude mice to evaluate hormonal carcinogenesis and regulation of benign prostate growth.

Tags

Keywords: Prostate CarcinogenesisBenign Prostatic HyperplasiaSex Steroid HormonesAndrogenEstrogenSubcutaneous Pellet ImplantationRenal Capsule XenograftingHormone RegulationProstate Cell RecombinantsImmunocompromised Mice

Article

Embed

ADD TO PLAYLIST

Usage Statistics

Related Videos

check_url/50574?article_type=v

Evaluation of Nanoparticle Uptake in Tumors in Real Time Using Intravital Imaging
check_url/50574?article_type=v

Teratoma Generation in the Testis Capsule
check_url/50574?article_type=v

Cell Population Analyses During Skin Carcinogenesis
check_url/50574?article_type=v

A Protocol for Genetic Induction and Visualization of Benign and Invasive Tumors in Cephalic Complexes of Drosophila melanogaster
check_url/50574?article_type=v

Evaluation of Tumor-infiltrating Leukocyte Subsets in a Subcutaneous Tumor Model
check_url/50574?article_type=v

Balloon-based Injury to Induce Myointimal Hyperplasia in the Mouse Abdominal Aorta
check_url/50574?article_type=v

Surgical Treatment for Benign Prostatic Hyperplasia: Holmium Laser Enucleation of the Prostate (HoLEP).
check_url/50574?article_type=v

Direct Drug Delivery to Kidney via the Renal Artery
check_url/50574?article_type=v

Repetitive Blood Sampling from the Subclavian Vein of Conscious Rat
check_url/50574?article_type=v

A Rat Orthotopic Renal Transplantation Model for Renal Allograft Rejection

Read Article