Debinding Sintering

Debinding sintering is a two-stage thermal processing method that converts a binder-containing powder compact into a dense ceramic or metal component. During debinding, solvents or controlled heating remove organic binders from the green part while preserving its shape; subsequent sintering heats the remaining powder below its melting point, allowing particles to diffuse, bond, and reduce porosity. Careful control of temperature, atmosphere, heating rate, and dimensional shrinkage helps prevent cracking, distortion, and residual contamination. In engineering, the process supports powder injection molding, material extrusion, and other powder-based manufacturing methods for producing complex, near-net-shape components.

Debinding Sintering - Related Videos

Research

JoVE Journal - Engineering

Spark Plasma Sintering Apparatus Used for the Formation of Strontium Titanate Bicrystals

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Cited by 5 •

2017

A viable technique for the formation of strontium titanate bicrystals at high pressure and fast heating rate via the spark plasma sintering apparatus is developed.

Research

JoVE Journal - Bioengineering
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Rapid Mix Preparation of Bioinspired Nanoscale Hydroxyapatite for Biomedical Applications

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Cited by 18 •

2017

This paper describes a novel method for the rapid manufacture of high quality bioinspired nanoscale hydroxyapatite. This biomaterial is of great significance in the manufacture of a wide range of innovative medical devices for clinical applications in orthopedics, craniofacial surgery and dentistry.

Mononuclear Cell Isolation from Mouse Brain: A Density Gradient Centrifugation Technique to Isolate Brain Resident Mononuclear Cells

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2023

In this video, we perform the isolation of mononuclear cells from a mouse’s brain using density gradient centrifugation. The isolated mononuclear cell suspension can be used for further downstream analysis.

A Direct, Early Stage Guanidinylation Protocol for the Synthesis of Complex Aminoguanidine-containing Natural Products

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Cited by 3 •

2016

Here, we present a protocol for direct, early stage guanidinylation that enables rapid total synthesis of aminoguanidine-containing small organic molecules. An advanced synthetic intermediate used in the synthesis of a blood coagulation factor XIa inhibitor was prepared using this protocol.

Preparation and In Vitro Characterization of Dendrimer-based Contrast Agents for Magnetic Resonance Imaging

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Cited by 5 •

2016

This protocol describes the preparation and characterization of a dendrimeric magnetic resonance imaging (MRI) contrast agent that carries cyclen-based macrocyclic chelates coordinating paramagnetic gadolinium ions. In a series of MRI experiments in vitro, this agent produced an amplified MRI signal when compared to the commercially available monomeric analogue.

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