Scanning Valve

A scanning valve is a mechanically or electronically actuated device that sequentially connects multiple fluid lines to a shared measurement or control circuit, reducing the need for separate instruments at every point. Its rotor, spool, or switching element aligns internal ports according to a programmed sequence, allowing a pressure sensor, analyzer, or sampling system to examine each channel under controlled timing and flow conditions. In engineering, scanning valves support automated pressure mapping, leak detection, process monitoring, and multi-point data acquisition. By consolidating measurements into one system, they can reduce hardware, simplify instrumentation, and improve repeatability, although valve response time, sealing, cross-contamination, and pressure compatibility must be managed.

Scanning Valve - Related Videos

Research

JoVE Journal - Developmental Biology
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Isolation and Characterization of Primary Rat Valve Interstitial Cells: A New Model to Study Aortic Valve Calcification

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Cited by 16 •

2017

This protocol describes the isolation, culture, and calcification of rat-derived valve interstitial cells, a highly physiological in vitro model of calcific aortic valve disease (CAVD). Exploitation of this rat model facilitates CAVD research in exploring the cell and molecular mechanisms that underlie this complex pathological process.

Education

JoVE Core - Molecular Biology

Leaky Scanning

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2020

During most eukaryotic translation processes, the small 40S ribosome subunit scans an mRNA from its 5' end until it encounters the first start AUG codon. The large 60S ribosomal subunit then joins the smaller one to initiate protein synthesis. The location of the translation initiation is largely determined by the nucleotides near the start codon as there may be multiple translation initiation sites present on the mRNA. Marilyn Kozak discovered that the sequence RCCAUGG (where R stands for...

Differential Scanning Calorimetry

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2023

Source: Danielle N. Beatty and Taylor D. Sparks, Department of Materials Science and Engineering, The University of Utah, Salt Lake City, UT Differential scanning calorimetry (DSC) is an important measurement to characterize thermal properties of materials. DSC is used primarily to calculate the amount of heat stored in a material as it heats up (heat capacity) as well as the heat absorbed or released during chemical reactions or phase changes. However, measurement of this heat can also lead to...

Isolation of Mouse Valve Interstitial Cells: An Enzymatic Method to Isolate and Culture VICs from Mouse Aortic Valve

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2025

In this video, we demonstrate the isolation of aortic valve interstitial cells from the heart of an adult mouse using a two-step collagenase procedure and their subsequent culture in low volume of growth media.

Heart Valves

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2025

The human heart is a complex organ with an intricate system of valves that regulate blood flow. There are two main types of valves: atrioventricular (AV) valves and semilunar valves. The AV valves prevent the backflow of blood from the ventricles to the atria during ventricular contraction. These valves function with the assistance of the chordae tendineae and papillary muscles. When the ventricles are relaxed, the chordae tendineae are slack, allowing blood to flow from the atria into the...

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