Electrospinning Apparatus Setup

Electrospinning apparatus setup is the arrangement of equipment used to produce continuous nanoscale fibers from a polymer solution or melt, a process important for creating materials that interact with biological systems. A syringe pump feeds the spinning fluid through a spinneret while a high-voltage source generates a Taylor cone and draws a charged jet toward a grounded collector; solvent evaporation or cooling solidifies the fibers during deposition. In genetics, these tunable fibrous scaffolds can support cell culture, tissue models, and localized delivery of nucleic acids or other biomolecules. Fiber diameter, alignment, porosity, and composition depend on voltage, flow rate, working distance, and solution properties.

Electrospinning Apparatus Setup - Related Videos

Research

JoVE Journal - Bioengineering
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Electrospinning Fundamentals: Optimizing Solution and Apparatus Parameters

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Cited by 93 •

2011

Electrospinning techniques can create a variety of nanofibrous scaffolds for tissue engineering or other applications. We describe here a procedure to optimize the parameters of the electrospinning solution and apparatus to obtain fibers with the desired morphology and alignment. Common problems and troubleshooting techniques are also presented.

Education

JoVE Science Education - Engineering

Electrospinning of Silk Biomaterials

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2023

Silk fibers have been processed and used to create fabrics and threads for centuries. However, the solubilizing of silk fibers, thereby turning it into a versatile pre-polymer solution is a much newer technology. Solubilized silk can be processed in many different ways to create a biocompatible material with controllable mechanical properties. This video introduces the processing of silk from silk worm cocoons, and shows how the silk solution can be used to create a fiber mat via...

Fabrication of Small Caliber Stent-grafts Using Electrospinning and Balloon Expandable Bare Metal Stents

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Cited by 10 •

2016

In the protocol, we present a method to manufacture a small caliber stent-graft by sandwiching a balloon expandable stent between two electrospun nanofibrous polyurethane layers.

Electrospinning of Photocatalytic Electrodes for Dye-sensitized Solar Cells

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Cited by 3 •

2017

The overall goal of this project was to use electrospinning to fabricate a photoanode with improved performance for dye-sensitized solar cells.

Research

JoVE Journal - Neuroscience
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Novel Apparatus and Method for Drug Reinforcement

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Cited by 9 •

2010

Operant drug self-administration and conditioned place preference (CPP) procedures are expansively used in research to model various components of drug reinforcement, consumption, and addiction in humans. In this report, we combined traditional CPP and self-administration methods as a novel approach to studying drug reinforcement and addiction in rats.

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