Point-of-care Diagnosis
Point-of-care Diagnosis - Related Videos
07:34
FISH for Pre-implantation Genetic Diagnosis
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Cited by 17 •
2011
This article describes the selection of suitable probes for single-cell FISH, spreading techniques for blastomere nuclei, and in situ hybridization and signal scoring, applied to pre-implantation genetic diagnosis (PGD) in a clinical setting.
01:21
Interdisciplinary Care: The Health Care Team-I
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2023
An interdisciplinary team includes many healthcare professionals working together and utilizing their skills, knowledge, and expertise to provide holistic and quality patient care. Physicians The physician's primary responsibility is to diagnose illness and direct the medical or surgical treatment of the condition. The authority to admit patients to a healthcare agency or institution and practice care within that setting is granted to physicians by the healthcare agency or institution itself.
01:18
Interdisciplinary Care: The Health Care Team-II
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2023
An interdisciplinary team includes many healthcare professionals working together and utilizing their skills, knowledge, and expertise to provide holistic and quality patient care. Here are a few more healthcare professionals. Physical Therapist A physical therapist (PT) aims to restore function or prevent additional impairment in a patient following an injury or disease. Massage, heat, cold, water, sonar waves, exercises, and electrical stimulation are some treatments used by PTs to treat...
01:25
Continuing Care
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2023
Continuing care describes the variety of health, personal, and social services provided over a prolonged period. The need for continuing care is increasing because people are living longer. Many people do not have families or others to care for them. Continuing care is mainly for patients who are disabled, functionally dependent, or suffering from a terminal disease. It is available within institutional settings or in homes. Examples include nursing centers or facilities, assisted living,...
01:22
Standards of Care I
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2024
Federal statutes profoundly impact nursing practice, providing critical guidelines to ensure patient care is equitable, accessible, and of the highest quality. The following laws address distinct aspects of healthcare provision and patient rights: • The Affordable Care Act (ACA), enacted in 2010 • The Americans with Disabilities Act (ADA), enacted in 1990 • The Emergency Medical Treatment and Active Labor Act (EMTALA) was enacted in 1986. The Affordable Care Act aims to transform...
FAQs
Antibody-antigen binding provides the recognition step in many immunology and infection assays. A test can use this interaction to identify a pathogen or detect an immune response in a specimen. Lateral-flow devices and other immunoassays translate that recognition into a result, making the biological target measurable close to clinical decision-making.
Nucleic-acid amplification approaches focus on pathogen genetic material rather than antibody-antigen recognition or an immune response. This distinction affects what the result means: amplification can indicate the presence of pathogen-associated nucleic acid, whereas immunoassays may detect either pathogen targets or host responses. Selecting between them therefore depends on the biological question being asked.
Assay reliability is shaped by sensitivity, specificity, and sample preparation, not simply by how quickly a result appears. Sensitivity and specificity help evaluate how consistently a test identifies its intended target, while preparation affects the specimen presented to the assay. Reviewing these factors is essential before applying results to treatment, triage, or infection-control decisions.
A basic workflow begins with collecting an appropriate specimen, such as blood, saliva, or a swab, followed by any required sample preparation. The prepared material is then assessed with a lateral-flow device, immunoassay, antibody-antigen format, or nucleic-acid amplification approach. The resulting information can support a clinical decision without waiting exclusively for centralized laboratory testing.
Point-of-care diagnosis is especially useful when rapid information can change immediate action. Results may support earlier treatment, infection control, triage, or monitoring, and the approach can be valuable where laboratory infrastructure is limited. In infection settings, testing specimens near patients can connect pathogen detection or immune-response measurement with decisions made during care.
Interpretation should link the detected signal to the question being asked. A pathogen-focused result and an immune-response result do not provide identical information, even when both come from a rapid assay. Researchers and clinicians therefore need to consider the target, specimen type, assay format, and sensitivity and specificity when using findings for clinical or public-health decisions.