Antral Follicle Count
Antral Follicle Count - Related Videos
05:10
Mouse Antral Oocyte Isolation: A Method to Isolate Antral Oocytes from Freshly Harvested Mouse Ovaries
0 Views •
2025
This video describes the isolation of antral oocytes from freshly harvested mouse ovaries. These antral oocytes can be used for further characterization and developmental studies.
09:30
In Vitro Culture Strategy for Oocytes from Early Antral Follicle in Cattle
0 Views •
Cited by 9 •
2020
We describe the procedures for isolation of growing oocytes from ovarian follicles at early stages of development, as well as the setup of an in vitro culture system which can support the growth and differentiation up to the fully-grown stage.
07:16
Isolation and Characterization of Mouse Antral Oocytes Based on Nucleolar Chromatin Organization
0 Views •
Cited by 17 •
2016
Here we present a protocol for the characterization of mouse antral oocytes based on nucleolar organization.
10:41
Culture and Co-Culture of Mouse Ovaries and Ovarian Follicles
0 Views •
Cited by 16 •
2015
This protocol describes the primary culture/co-culture of mouse ovarian tissue, using ovaries from neonatal mice and individual ovarian follicles from prepubertal mice. The culture techniques support development in a highly physiological manner, allowing investigation of the effect of extrinsic agents on the ovary, and of interactions between ovarian follicles.
06:36
Extraction, Labeling, and Purification of Lineage-Specific Cells from Human Antral Follicles
0 Views •
2022
Here, we present protocols for the identification and purification of ovarian cells from antral follicles. We elaborate on methods for processing whole ovaries for the cryopreservation of cortical strips while also harvesting intact antral follicles that are treated enzymatically to liberate multiple follicle resident cell types, including granulosa, theca, endothelial, hematopoietic, and stromal cells.
FAQs
Antral follicle count is most useful as an estimate of ovarian reserve, not as an isolated conclusion about reproductive potential. The result indicates how large the pool of follicles may be that can respond to stimulation, while age, hormone testing, and clinical history add necessary context. This combined interpretation helps clinicians avoid basing fertility evaluation on one measurement alone.
The 2–10 mm size range focuses the assessment on small antral follicles visible during the relevant part of the cycle. Counting follicles within a defined size range links the ultrasound finding to the population considered capable of responding to stimulation. Consequently, the measurement is used to anticipate response rather than simply to describe the ovary’s appearance.
An unusually high or low AFC can provide clinically relevant context, but the count itself does not establish a specific condition. Instead, it signals that clinicians should interpret ovarian findings alongside the rest of the fertility assessment. This is useful when evaluating patterns associated with altered follicle numbers or interpreting findings that may affect treatment planning.
Clinicians obtain AFC with transvaginal ultrasound during the early follicular phase. The scan identifies the small fluid-filled follicles visible in the ovaries, and the clinician records their number within the relevant size range. Performing the assessment at this cycle stage provides a consistent point for fertility evaluation and treatment planning.
During assisted reproductive treatment, AFC helps estimate how the ovaries may respond to stimulation. Clinicians can use that estimate when planning medication, while recognizing that the count is an estimate rather than a guaranteed response. Its practical value is prospective: it informs an initial treatment strategy that can be interpreted with subsequent clinical information.
An AFC result should be read together with age, hormone tests, and clinical history. These additional factors help place the ultrasound count in context and prevent an apparently high or low value from being interpreted in isolation. In medicine, this integrated approach supports both fertility evaluation and decisions about assisted reproductive treatment without treating one measurement as definitive.