Disease Diagnosis
Disease Diagnosis - Related Videos
09:20
Microwave Assisted Rapid Diagnosis of Plant Virus Diseases by Transmission Electron Microscopy
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Cited by 16 •
2011
This study describes a method that allows the rapid and clear diagnosis of plant virus diseases in about half a day by using a combination of microwave assisted plant sample preparation for transmission electron microscopy and negative staining methods.
07:34
FISH for Pre-implantation Genetic Diagnosis
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Cited by 17 •
2011
This article describes the selection of suitable probes for single-cell FISH, spreading techniques for blastomere nuclei, and in situ hybridization and signal scoring, applied to pre-implantation genetic diagnosis (PGD) in a clinical setting.
06:23
The 4 Mountains Test: A Short Test of Spatial Memory with High Sensitivity for the Diagnosis of Pre-dementia Alzheimer's Disease
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Cited by 68 •
2016
This article describes the 4 Mountains Test (4MT), a hippocampus-dependent test of working allocentric spatial memory. The hippocampus is affected early in Alzheimer's disease (AD) and this article outlines the 4MT methodology and results of patient testing, which demonstrates the value of the 4MT in the diagnosis of pre-dementia AD.
01:22
Nursing Diagnosis
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2023
Following assessment, a nursing diagnosis is the next step in the nursing process. It begins after the nurse has collected and recorded the patient data. The purpose of diagnosing is to identify how the client responds to actual or potential health processes, identify factors that bestow or that cause health problems, the etiologies, and identify resources or strengths the individual, group, or community can draw on to prevent or resolve problems. The nursing diagnosis focuses on evidence-based...
10:47
An Overview of Genetics and Disease
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2023
Many human diseases are associated with mutations or variations in genetic sequences. Some of these genetic variants are heritable, passed down from generation to generation, while others arise sporadically during an organism’s life and cause diseases such as cancer. Researchers are trying to identify and characterize these genetic alterations in the hopes of improving diagnosis and therapeutic options for patients.In this video, we will examine the history of genetic disease research, and...
FAQs
A differential diagnosis keeps clinicians from committing too early to a single explanation. They compare several conditions that could account for the patient’s symptoms, history, physical findings, and test results, then identify which diagnosis best fits the complete pattern. This approach is especially important when different disorders produce similar findings but require different management.
A test result gains meaning from the broader clinical pattern rather than standing alone. Symptoms, previous medical information, and physical findings help clinicians judge whether laboratory, imaging, pathology, or other results support a suspected condition. Combining these evidence sources can clarify ambiguous findings and reduce the risk of selecting a diagnosis that does not explain the patient’s presentation.
New information can alter the relative support for competing diagnoses. Additional clinical findings, test results, or specialized assessments may strengthen one explanation, weaken another, or reveal that the initial interpretation was incomplete. Diagnostic reasoning therefore remains responsive to evidence, allowing clinicians to refine the working conclusion as the patient’s evaluation develops.
Clinicians compare the full pattern of findings rather than relying on one shared symptom. Differences in medical history, physical examination, laboratory analyses, imaging, pathology, or other assessments may separate conditions that initially appear alike. Making that distinction matters because similar presentations can correspond to different management needs and may lead to different expectations about disease progression.
The workflow begins with information from symptoms, medical history, and physical findings. Clinicians then develop possible explanations, select or review relevant clinical assessments, and compare the resulting evidence with each candidate condition. Laboratory analyses, imaging, pathology, and other tests can refine the assessment, after which the diagnosis may be revised when additional information becomes available.
These assessment types provide complementary evidence for clinical reasoning. Laboratory analyses contribute results from examined samples, imaging supplies views of internal findings, and pathology provides information from tissue or other examined material. Other assessments may add further clinical evidence. Their value comes from integrating the results with the patient’s presentation, not from treating any one modality as sufficient in every case.
A well-supported diagnosis helps guide treatment selection and contributes to estimating how a disease may progress. It also supports timely intervention, separates conditions with different management requirements, and provides a basis for disease surveillance and medical research. At the individual level, this can improve care decisions; at the population level, diagnostic information can help track disease patterns.