Image Guided Tumor Ablation

Image-guided tumor ablation is a minimally invasive treatment that uses medical imaging to locate tumors and direct energy-delivery probes with precision. During the procedure, ultrasound, computed tomography, or magnetic resonance imaging guides probe placement, while heat, extreme cold, or other energy disrupts tumor tissue and produces localized cell death. Clinicians use techniques such as radiofrequency ablation, microwave ablation, and cryoablation to treat selected tumors, often when surgery is unsuitable or preservation of surrounding tissue is important. Imaging also supports real-time monitoring, treatment planning, and follow-up, making ablation valuable in interventional oncology and personalized cancer care.

Image Guided Tumor Ablation - Related Videos

Research

JoVE Journal - Medicine
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Thermal Ablation for the Treatment of Abdominal Tumors

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Cited by 19 •

2011

A thermal tumor ablation procedure is described. The entire procedure is detailed, including pretreatment planning and imaging studies, anesthesia, adjuvant techniques to facilitate a percutaneous approach, imaging guidance of the ablation device to the tumor, thermal treatment, post-treatment care and follow-up.

Research

JoVE Journal - Medicine
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Dynamic Lung Tumor Tracking for Stereotactic Ablative Body Radiation Therapy

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Cited by 9 •

2015

Stereotactic ablative body radiation therapy (SBRT) involves the precise delivery of high-dose radiation to cancer tumor targets. A novel SBRT platform offers a first-of-its-kind gimbaled radiation accelerator mounted within a pivoting O-ring gantry capable of dynamic image-guided tumor tracking. Here, we describe dynamic tumor tracking for lung targets.

Research

JoVE Journal - Bioengineering

One Minute, Sub-One-Watt Photothermal Tumor Ablation Using Porphysomes, Intrinsic Multifunctional Nanovesicles

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Cited by 14 •

2013

We developed novel intrinsic multifunctional nanovesicles called porphysomes, which have structure-dependent fluorescence self-quenching and unique photothermal properties, thus functioning as potent photothermal therapy agents. We formulated porphysomes using high pressure extrusion and investigated their photothermal therapy efficacy in a xenograft tumor model.

Laser Interstitial Thermal Therapy for Intracranial Tumor Ablation in a Human Patient

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2025

Begin with an anesthetized human patient with an exposed skull. The patient is diagnosed with an intracranial tumor.Drill into the exposed skull to create a hole, generating an access point.Using stereotactic guidance, insert a laser diffusing fiber or LDF along the predetermined path and secure it in place.Transfer the patient to an MRI scanner and connect the LDF to a laser source.Capture MRI images from multiple angles to visualize the fiber path and the tumor.This confirms the LDF’s...

Irreversible Electroporation: A Technique for Ablating Pancreatic Tumor in Mouse

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2023

This video describes the procedure for performing irreversible electroporation (IRE) for non-thermal ablation of pancreatic tumors in mice. Both subcutaneous (SQ) and orthotopic tumors can be successfully treated with IRE in a highly controlled setting, facilitating various studies post-procedure.

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