Ivc Ligation Procedure

The IVC ligation procedure is a surgical technique that permanently occludes the inferior vena cava, the major vein returning blood from the lower body to the heart. By interrupting venous flow through the vessel, the procedure can reduce passage of thrombi from the lower extremities into the pulmonary circulation, while blood is redirected through collateral veins. Historically used for pulmonary embolism prevention and applied in selected cases of severe trauma or vascular disease, IVC ligation requires careful assessment because impaired venous drainage can cause leg swelling, venous hypertension, and long-term circulatory complications. Understanding its mechanism supports safer surgical decision-making and postoperative monitoring.

Ivc Ligation Procedure - Related Videos

Research

JoVE Journal - Medicine

Cecal Ligation Puncture Procedure

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Cited by 200 •

2011

The mouse model of cecal ligation and puncture as a valuable tool for the study of human sepsis.

Rat Model of the Associating Liver Partition and Portal Vein Ligation for Staged Hepatectomy (ALPPS) Procedure

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Cited by 6 •

2017

Inducing rapid liver hypertrophy using Associating Liver Partition and Portal vein ligation for a Staged hepatectomy (ALPPS) has been proposed for resection of borderline resectable liver tumors. This model may elucidate mechanisms involved in rapid hypertrophy and allows testing of drugs that promote or block the acceleration of regeneration.

Education

JoVE Science Education - Basic Biology

DNA Ligation Reactions

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2023

In molecular biology, ligation refers to the joining of two DNA fragments through the formation of a phosphodiester bond. An enzyme known as a ligase catalyzes the ligation reaction. In the cell, ligases repair single and double strand breaks that occur during DNA replication. In the laboratory, DNA ligase is used during molecular cloning to join DNA fragments of inserts with vectors – carrier DNA molecules that will replicate target fragments in host organisms. This video provides an...

An Experimental Model of Peripheral Ischemia: A Procedure to Generate Peripheral Ischemia via Femoral Artery Ligation in a Rabbit

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2025

In this video, we demonstrate a surgical procedure to induce peripheral ischemia via femoral artery ligation in a rabbit. This method provides an effective experimental model for peripheral vascular disease research.

Modified Technique for Coronary Artery Ligation in Mice

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Cited by 8 •

2013

The surgical procedure used to induce experimental myocardial infarction in mice begins with left thoracotomy between the third and the fourth ribs in order to visualize the anterior surface of the heart and left lung. The left coronary artery is ligated, the chest is closed and the mouse is allowed to recover spontaneously.

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