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Modified Technique for Coronary Artery Ligation in Mice
JoVE Journal
Medicine
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JoVE Journal Medicine
Modified Technique for Coronary Artery Ligation in Mice

Modified Technique for Coronary Artery Ligation in Mice

25,254 Views

05:47 min

March 29, 2013

DOI:

05:47 min
March 29, 2013

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Summary

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The surgical procedure used to induce experimental myocardial infarction in mice begins with left thoracotomy between the third and the fourth ribs in order to visualize the anterior surface of the heart and left lung. The left coronary artery is ligated, the chest is closed and the mouse is allowed to recover spontaneously.

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