Lymphatic Vessel Anastomosis

Lymphatic vessel anastomosis is a surgical or microsurgical connection between lymphatic vessels that restores continuity of the lymphatic network after injury or disruption. By carefully aligning and joining vessel ends, surgeons create a patent channel through which lymph can move, helping bypass obstruction and reestablish drainage from affected tissues. In medicine, this technique supports treatment of selected cases of secondary lymphedema, postoperative lymphatic injury, and other disorders involving impaired lymph flow, while microsurgical imaging and intraoperative assessment help identify suitable vessels and evaluate repair success.

Lymphatic Vessel Anastomosis - Related Videos

Research

JoVE Journal - Medicine

Vessel-sparing Excision and Primary Anastomosis

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Cited by 6 •

2019

Here, we present an elaborate and efficient protocol to treat isolated short bulbar or posterior urethral strictures with vessel-sparing excision and primary anastomosis.

Education

JoVE Core - Anatomy and Physiology

Lymphatic Vessels and Lymph Transport

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2024

Lymphatic vessels, known as lymphatics, are crucial in transporting lymph from peripheral tissues to our venous system. This process begins with lymph entering through tiny capillaries that branch through tissues. These capillaries have unique features such as larger diameters, thinner walls, and a distinctive one-way valve system formed by overlapping endothelial cells. This one-way system allows fluids, solutes, and even pathogens to enter but prevents their return to the intercellular spaces.

Non-invasive Optical Imaging of the Lymphatic Vasculature of a Mouse

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Cited by 25 •

2013

Recently developed imaging techniques using near-infrared fluorescence (NIRF) may help elucidate the role the lymphatic system plays in cancer metastasis, immune response, wound repair, and other lymphatic-associated diseases.

Measurement of Cytosolic Ca2+ in Isolated Contractile Lymphatics

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Cited by 24 •

2011

We introduce an approach to evaluate the cytosolic Ca2+ concentration in isolated lymphatics to study Ca2+-dependent and Ca2+-sensitizing mechanisms of lymphatic smooth muscle contraction.

Quantifying Leukocyte Egress via Lymphatic Vessels from Murine Skin and Tumors

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Cited by 23 •

2019

Here, we demonstrate the methods for in vivo quantification of leukocyte egress from naïve, inflamed, and malignant murine skin. We perform a head-to-head comparison of two models: transdermal FITC application and in situ photoconversion. Furthermore, we demonstrate the utility of photoconversion for tracking leukocyte egress from cutaneous tumors.

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