Skin Cancer Detection

Skin cancer detection is the process of identifying suspicious changes in the skin that may indicate melanoma or other forms of skin cancer, supporting timely diagnosis and treatment. Clinicians assess lesions through a visual skin examination and dermoscopy, which magnifies surface structures, while a biopsy provides tissue for microscopic evaluation when malignancy is suspected. Detection methods help distinguish benign from cancerous lesions, guide clinical decisions, and improve recognition of disease at an earlier stage. In medicine, combining patient history, lesion monitoring, imaging, and histopathology strengthens diagnostic accuracy and supports research into more effective screening approaches.

Skin Cancer Detection - Related Videos

Research

JoVE Journal - Medicine
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Quantitative Visualization and Detection of Skin Cancer Using Dynamic Thermal Imaging

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2011

We demonstrated that malignant pigmented lesions with increased metabolic activity generate quantifiable amounts of heat and the measurement of the transient thermal response of the skin to a cooling excitation allows quantitative identification of melanoma and other skin cancers (vs. non-proliferative nevi) at an early stage of the disease.

Education

JoVE Core - Anatomy and Physiology

Skin Cancer

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2023

Skin cancer is a type of cancer that occurs when there is an abnormal growth of skin cells, usually triggered by damage to the DNA within the skin cells. It is primarily caused by exposure to ultraviolet (UV) radiation from the sun or artificial sources like tanning beds. Skin cancer is the most common type of cancer worldwide, and its incidence continues to rise. Basal Cell Carcinoma (BCC): BCC is the most common type of skin cancer, accounting for about 80% of cases. It typically develops in...

Chemical-induced Two-stage Skin Carcinogenesis Model: An Experimental In Vivo Mouse Model of Skin Cancer

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2023

This video describes the procedure to induce two-stage skin carcinogenesis to study tumor initiation by topical application of chemicals. In the first step, a mutagen, DMBA, is applied onto the skin of a mouse model which initiates tumor formation by causing mutations in the stem cells, followed by the application of a growth stimulator, TPA, which accelerates skin papilloma formation.

Detection of Targetable Alterations in Non-small Cell Lung Cancer using Next-generation Sequencing

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2025

This protocol describes an automated, ISO15189-accredited next-generation sequencing workflow for detecting targetable genomic alterations in non-small cell lung cancer (NSCLC) formalin-fixed paraffin-embedded tissues.

SCAnED - An Open-source Skin Segmentation Macro for Semi-automated Cell and Nuclei Detection in Epidermal and Dermal Skin Compartments

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2025

Here, we present a semi-automated protocol for identifying and quantifying immune and non-immune cells in skin sections using SCAnED, a free ImageJ-based macro for skin segmentation.

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