Vascular Coupling Device

A vascular coupling device is a microsurgical instrument used to join two blood vessels and restore a continuous pathway for blood flow, often without conventional suturing. During the procedure, the surgeon places the vessel ends over small pins on two coupling rings, everts the vessel walls, and brings the rings together so the aligned edges form an anastomosis. These devices are used primarily for venous anastomoses in reconstructive and plastic surgery, including free-flap procedures, where reliable vessel connection is essential for tissue survival. Their standardized alignment can support efficient surgery and consistent vascular patency.

Vascular Coupling Device - Related Videos

Research

JoVE Journal - Engineering

Thermal Measurement Techniques in Analytical Microfluidic Devices

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Cited by 6 •

2015

Here, we present three protocols for thermal measurements in microfluidic devices.

Perfusable Vascular Network with a Tissue Model in a Microfluidic Device

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Cited by 10 •

2018

The protocol describes how to engineer a perfusable vascular network in a spheroid. The spheroid's surrounding microenvironment is devised to induce angiogenesis and connect the spheroid to the microchannels in a microfluidic device. The method allows the perfusion of the spheroid, which is a long-awaited technique in three-dimensional cultures.

Education

JoVE Core - Analytical Chemistry

Spin–Spin Coupling: Two-Bond Coupling (Geminal Coupling)

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2024

Two NMR-active nuclei bonded to a central atom can be involved in geminal or two-bond coupling. Geminal coupling is commonly seen between diastereotopic protons in chiral molecules and unsymmetrical alkenes, among others. The central atom need not be NMR-active because its electrons are affected by the electron polarization of the spin-active atoms. However, spin information is transmitted less effectively than in one-bond coupling, and 2J values are usually weaker than 1J values. The energy of...

Spin–Spin Coupling: Three-Bond Coupling (Vicinal Coupling)

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2024

Vicinal or three-bond coupling is commonly observed between protons attached to adjacent carbons. Here, nuclear spin information is primarily transferred via electron spin interactions between adjacent C‑H bond orbitals. This generally favors the antiparallel arrangement of spins, so 3J values are usually positive. The extent of coupling depends on the C‑C bond length, the two H‑C‑C angles, any electron-withdrawing substituents, and the dihedral angle between the involved orbitals. The...

Palladium-Catalyzed Cross Coupling

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2023

Source: Vy M. Dong and Faben Cruz, Department of Chemistry, University of California, Irvine, CA This experiment will demonstrate the concept of a palladium-catalyzed cross coupling. The set-up of a typical Pd-catalyzed cross coupling reaction will be illustrated. Pd-catalyzed cross coupling reactions have had a profound effect on how synthetic chemists create molecules. These reactions have enabled chemists to construct bonds in new and more efficient ways. Such reactions have found widespread...

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