Photo Beam Arrays

Photo beam arrays are coordinated sets of light beams arranged to illuminate multiple defined regions with controlled intensity, wavelength, and timing. In pharmacology, they can regulate photoresponsive compounds by delivering light that triggers photochemical activation, inactivation, or release of a drug at selected locations. This spatial and temporal control enables researchers to examine receptor signaling, cellular responses, and localized drug action while limiting exposure in neighboring regions. Photo beam arrays therefore support precise studies of dose, timing, and distribution, and may contribute to improved experimental models and therapies that use light to control pharmacological effects.

Photo Beam Arrays - Related Videos

Research

JoVE Journal - Neuroscience

Using Affordable LED Arrays for Photo-Stimulation of Neurons

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Cited by 7 •

2011

Adult-born neurons expressing ChR2 can be manipulated in slice electrophysiological preparations in order to examine their contribution towards the function of olfactory neural circuits.

Polymeric Microneedle Array Fabrication by Photolithography

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Cited by 24 •

2015

Here, we present a protocol describing a mold-free fabrication process of the polymeric microneedles by photolithography.

Submillisecond Conformational Changes in Proteins Resolved by Photothermal Beam Deflection

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Cited by 1 •

2014

Here we report an application of the photothermal beam deflection technique in combination with a caged calcium compound, DM-nitrophen, to monitor microsecond and millisecond dynamics and energetics of structural changes associated with the calcium association to a neuronal calcium sensor, Downstream Regulatory Element Antagonist Modulator.

Education

JoVE Science Education - Engineering

Focused Ion Beams

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2023

Source: Sina Shahbazmohamadi and Peiman Shahbeigi-Roodposhti-Roodposhti, School of Engineering, University of Connecticut, Storrs, CT As electron microscopes become more complex and widely used in research labs, it becomes more of a necessity to introduce their capabilities. Focused ion beam (FIB) is an instrument that can be employed in order to fabricate, trim, analyze and characterize materials on mico- and nano-scales in a wide variety of fields from nano-electronics to medicine. FIB...

Beams

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2023

Beams are integral components of structural engineering and construction, designed to support loads applied at various points along their length. These long, straight members can be classified based on geometry, cross-section, support type, and equilibrium condition. Based on geometry, beams can be straight, tapered, or curved. Straight beams are the most common type and have a constant cross-section throughout their length. Tapered beams, on the other hand, have a varying cross-section along...

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