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Cancer Research

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JoVE Journal Cancer Research

Microfluidic Shear Apparatus Setup for Single-Cell Fluid Shear Assay (Video) | JoVE

Inferior Vena Cava (IVC) Ligation for Venous Thrombosis Analysis in Mouse (Video) | JoVE

Journal (Cancer Research)

Inferior Vena Cava (IVC) Ligation for Venous Thrombosis Analysis in Mouse (Video) | JoVE

Real Time Detection of In Vitro Tumor Cell Apoptosis Induced by CD8+ T Cells to Study Immune Suppressive Functions of Tumor-infiltrating Myeloid Cells

Journal (Cancer Research)

Real Time Detection of In Vitro Tumor Cell Apoptosis Induced by CD8⁺ T Cells to Study Immune Suppressive Functions of Tumor-infiltrating Myeloid Cells

Microfluidic Shear Apparatus Setup for Single-Cell Fluid Shear Assay (Video) | JoVE

Enhancing Targeted Cancer Diagnosis by Quantifying Single-Cell Mechanics

Article DOI: 10.3791/200187-v • 02:16 min • May 19th, 2023

May 19th, 2023 •

Luke J. Holen*¹, Killian Onwudiwe*¹, Julian Najera¹, Maksym Zarodniuk¹, John D. Obayemi², Winston O. Soboyejo², Meenal Datta¹

¹Department of Aerospace and Mechanical Engineering, University of Notre Dame, ²Departments of Mechanical and Biomedical Engineering, Worcester Polytechnic Institute

* These authors contributed equally

Tags

Shear Assay Protocol Single-cell Material Properties Cancer Research Mechanical Properties Shear Forces Immune System Microfluidic Devices High-throughput Techniques Cellular Deformability Viscoelastic Properties Biomarkers Early Cancer Diagnosis Tumor Microenvironment Scaling Throughput Clinical Translation Standardization Reproducibility Multimodal Data Mechanical Stressors Structural Integrity Cytoskeletal Proteins Filamentous Actin

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