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Biochemistry

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JoVE Journal Biochemistry

Running the mAbscale Application to Calculate the Masses of Monoclonal Antibody-Based Protein Therapeutics (Video) | JoVE

In Situ Measurement and Correlation of Cell Density and Light Emission of Bioluminescent Bacteria

Journal (Biochemistry)

In Situ Measurement and Correlation of Cell Density and Light Emission of Bioluminescent Bacteria

Analysis of Fluorescent-Stained Lipid Droplets with 3D Reconstruction for Hepatic Steatosis Assessment (Video) | JoVE

Journal (Biochemistry)

Analysis of Fluorescent-Stained Lipid Droplets with 3D Reconstruction for Hepatic Steatosis Assessment (Video) | JoVE

Running the mAbscale Application to Calculate the Masses of Monoclonal Antibody-Based Protein Therapeutics (Video) | JoVE

A Python-Based Tool for Accurate Mass Calculation of Biotherapeutic Entities

Article DOI: 10.3791/200341-v • 03:04 min • June 16th, 2023

June 16th, 2023 •

Thomas Harkins^1,2, Li Cao¹, Kshitij Khatri^1,3

¹GlaxoSmithKline, ²Merck, ³Moderna

Tags

Open-source Framework Mass Calculation Antibody-based Therapeutic Molecules Biotherapeutic Masses Mass Spectrometry Protein Subunits Biopharmaceutical Development Computational Tools Protein And Peptide Molecular Weights Biotherapeutic Entities Modular Mass Calculation Routine Therapeutic Glycoproteins Monoclonal Antibodies Bispecific Antibodies Antibody-drug Conjugates Python-based Calculation Framework Vaccines Fusion Proteins Oligonucleotides Top-down Mass Spectrometry Data Standalone Desktop Application Graphical User Interface (GUI)

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