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Media Preparation for Setting Up the All-Human 2D+ Hepatic Culture System (Video) | JoVE

A Physiologically-Relevant All-Human 2D+ Hepatic System for Drug Discovery

Article DOI: 10.3791/200767-v • 01:12 min • October 20th, 2023
October 20th, 2023 •
1, 2, 3, 4, 1, 1
1Institute of Regenerative Medicine, LifeNet Health, 2Biologics Division, LifeNet Health, 3LifeSciences Division, LifeNet Health, 4Research and Development, LifeSciences, LifeNet Health

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Volledig menselijk leverkweeksysteem Geneesmiddelenontwikkeling Primaire menselijke hepatocyten Farmacologische studies Toxicologische studies In Vitro Modelplatforms Fenotypische stabiliteit Experimentele reproduceerbaarheid Ontdooien Plateren Onderhoud Tweedimensionale kweektechnieken Driedimensionale systemen Gehechtheid Plateerbaarheid Zaaidichtheid Functionaliteit Langdurige kweek Hepatocytkolonies Leverspecifieke marker Levensvatbaarheid Architecturale integriteit Albumineniveaus Ureumniveaus Farmacologische toepassingen toxicologische toepassingen
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