Waiting
Login-Verarbeitung ...

Trial ends in Request Full Access Tell Your Colleague About Jove
Journal / Immunology and Infection / Chemoselective Modification of Viral Surfaces via …
JoVE Journal
Immunology and Infection
Author Produced

Ein Abonnement für JoVE ist erforderlich, um diesen Inhalt ansehen zu können.

JoVE Journal Immunology and Infection
Chemoselective Modification of Viral Surfaces via Bioorthogonal Click Chemistry
A Photodynamic Approach to Study Function of Intracellular Vesicle Rupture
Journal (Immunology and Infection)
A Photodynamic Approach to Study Function of Intracellular Vesicle Rupture
Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice
Journal (Immunology and Infection)
Recurrent Escherichia coli Urinary Tract Infection Triggered by Gardnerella vaginalis Bladder Exposure in Mice
 

Chemoselective Modification of Viral Surfaces via Bioorthogonal Click Chemistry

Article DOI: 10.3791/4246-v • 12:32 min • August 19th, 2012
August 19th, 2012 •
1, 1, 1, 1, 1
1Department of Chemistry, Stony Brook University

Kapitel

Summary
Automatic Translation

Adenovirus particles are engineered to contain either the unnatural amino acid analogue azidohomoalanine or the azido sugar O-GlcNAz. The azide group of each is chemoselectively ligated via "click" chemistry reactions as a means of viral surface modification.

Tags

Chemoselective Modification Viral Surfaces Bioorthogonal Click Chemistry Gene Therapy Oncolytic Applications Vaccine Development Genetics-based Approaches Chemoselective Ligation Targeting Molecules Dyes Azide Tags Metabolic Labeling Effector Ligands Adenovirus Particles Azidohomoalanine O-linked N-azidoacetylglucosamine
Read Article

Get cutting-edge science videos from JoVE sent straight to your inbox every month.

Waiting X
Simple Hit Counter