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Quantitative Analysis and Characterization of Atherosclerotic Lesions in the Murine Aortic Sinus
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Quantitative Analysis and Characterization of Atherosclerotic Lesions in the Murine Aortic Sinus

Article DOI: 10.3791/50933-v • 06:43 min • December 7th, 2013
December 7th, 2013 •
1, 1, 2, 2, 1,2
1Department of Biochemistry and Biomedical Sciences, McMaster University, 2Thrombosis and Atherosclerosis Research Institute, McMaster University

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Summary
Automatic Translation

We describe procedures to quantify and characterize atherosclerotic lesions in mouse models using precision sectioning of the aortic sinus and ascending aorta combined with histochemical and immunohistochemical analysis.

Tags

Quantitative Analysis Characterization Atherosclerotic Lesions Murine Aortic Sinus Myocardial Infarction Stroke Mouse Models Molecular Pathophysiology Cellular Pathophysiology Cross-sectional Area Total Volume Atherosclerotic Progression Treatment Groups Valve Leaflets Sectioning Angle Staining Methods Atherogenesis
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