Myelin Oligodendrozyten Glykoprotein (MOG<sub> 35-55</sub>) Induzierten experimentellen autoimmunen Enzephalomyelitis (EAE) in C57BL / 6 Mäuse
81,900 Views
•
08:03 min
•
April 15, 2014
DOI:
Summary
Automatically generated
Experimentelle Autoimmun-Enzephalomyelitis (EAE) ist ein etabliertes Tiermodell für multiple Sklerose. C57BL / 6 Mäuse mit Myelin-Oligodendrozyten-Glykoprotein (MOG)-Peptid 35-55 (MOG 35-55) immunisiert, was zu einer aufsteigenden schlaffen Lähmung durch autoreaktive Immunzellen im zentralen Nervensystem verursacht. Protokolle für die Krankheitsinduktion und Überwachung diskutiert.
Verwandte Videos
08:38
Overcoming Unresponsiveness in Experimental Autoimmune Encephalomyelitis (EAE) Resistant Mouse Strains by Adoptive Transfer and Antigenic Challenge
Verwandte Videos
20352 Views
08:47
Induction of Experimental Autoimmune Encephalomyelitis in Mice and Evaluation of the Disease-dependent Distribution of Immune Cells in Various Tissues
Verwandte Videos
23710 Views
10:47
Simple and Efficient Production and Purification of Mouse Myelin Oligodendrocyte Glycoprotein for Experimental Autoimmune Encephalomyelitis Studies
Verwandte Videos
10971 Views
10:50
Visualizing Impairment of the Endothelial and Glial Barriers of the Neurovascular Unit during Experimental Autoimmune Encephalomyelitis In Vivo
Verwandte Videos
7706 Views
09:46
Rat Model of Widespread Cerebral Cortical Demyelination Induced by an Intracerebral Injection of Pro-Inflammatory Cytokines
Verwandte Videos
4695 Views
05:44
A Rapid, Simple, and Standardized Homogenization Method to Prepare Antigen/Adjuvant Emulsions for Inducing Experimental Autoimmune Encephalomyelitis
Verwandte Videos
3483 Views
05:55
Quantification of Autoreactive Antibodies in Mice upon Experimental Autoimmune Encephalomyelitis
Verwandte Videos
801 Views
05:44
Modeling Multiple Sclerosis in the Two Sexes: MOG35-55-Induced Experimental Autoimmune Encephalomyelitis
Verwandte Videos
1348 Views
08:03
Myelin Oligodendrocyte Glycoprotein (MOG35-55) Induced Experimental Autoimmune Encephalomyelitis (EAE) in C57BL/6 Mice
Verwandte Videos
81.9K Views
13:02
Sagittal Plane Kinematic Gait Analysis in C57BL/6 Mice Subjected to MOG35-55 Induced Experimental Autoimmune Encephalomyelitis
Verwandte Videos
8.6K Views
Read Article
Cite this Article
Bittner, S., Afzali, A. M., Wiendl, H., Meuth, S. G. Myelin Oligodendrocyte Glycoprotein (MOG35-55) Induced Experimental Autoimmune Encephalomyelitis (EAE) in C57BL/6 Mice. J. Vis. Exp. (86), e51275, doi:10.3791/51275 (2014).
Copy