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Preparing a 68Ga-labeled Arginine Glycine Aspartate (RGD)-peptide for Angiogenesis
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Preparing a 68Ga-labeled Arginine Glycine Aspartate (RGD)-peptide for Angiogenesis

Article DOI: 10.3791/58218-v • 07:48 min • January 7th, 2019
January 7th, 2019 •
1, 1, 1, 1, 1, 1
1Division of Applied RI, Korea Institute of Radiological and Medical Sciences

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Summary
Automatic Translation

The αvβ3 integrin is a type of adhesion protein that is highly expressed on activated endothelial cells undergoing angiogenesis. Thus, evaluating the integrity of the integrin is of great interest in oncology. Here, we introduce a method to prepare 68Ga-labeled radiopeptides and a method to assess its biological effectiveness.

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68Ga-labeled Arginine Glycine Aspartate (RGD)-peptide Angiogenesis Preparation Method Biological Evaluation Radiometal-labeled Peptide Hydrochloric Acid Gallium Trichloride Gallium Germanium Generator Nitrogen Gas Sodium Acetate High Performance Liquid Chromatography C18 Column Reverse-phased Cartridge Saline Ethanol Reconstitution PBS Sterile Strainer
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