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Neuroscience

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Labeling and Imaging of Amyloid Plaques in Brain Tissue Using the Natural Polyphenol Curcumin
 

Labeling and Imaging of Amyloid Plaques in Brain Tissue Using the Natural Polyphenol Curcumin

Article DOI: 10.3791/60377-v 10:15 min November 1st, 2019
November 1st, 2019

Kapitel

Summary

Curcumin is an ideal fluorophore for labeling and imaging of amyloid beta protein plaques in brain tissue due to its preferential binding to amyloid beta protein as well as its structural similarities with other traditional amyloid binding dyes. It can be used to label and image amyloid beta protein plaques more efficiently and inexpensively than traditional methods.

Tags

Keywords: Amyloid Plaques Curcumin Brain Tissue Labeling Imaging Alzheimer's Disease Parkinson's Disease Huntington's Disease Perfusion Cryostat Sectioning
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