Semi-quantitative Bestimmung der dopaminergen Neuronendichte in der Substantia Nigra von Nagetiermodellen mittels automatisierter Bildanalyse
4.1K Aufrufe
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Zitiert von 6
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06:09 Min.
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2. Februar 2021
DOI :10.3791/62062-v
2. Februar 2021
•4.1K Aufrufe
Darren M. O'Hara1,2 , Minesh Kapadia1,2 , Susan Ping1,2 , Suneil K. Kalia1,2,3 , Lorraine V. Kalia1,2,4,5,6
1Krembil Research Institute, Toronto Western Hospital, University Health Network, 2Department of Laboratory Medicine and Pathobiology, University of Toronto, 3Department of Surgery, Division of Neurosurgery, University of Toronto, 4Department of Medicine, Division of Neurology, University of Toronto, 5Department of Medicine, Division of Neurology, Edmond J. Safra Program in Parkinson's Disease and the Morton and Gloria Shulman Movement Disorders Clinic, Toronto Western Hospital, University Health Network, 6Tanz Centre for Research in Neurodegenerative Diseases, University of Toronto
Hier stellen wir eine automatisierte Methode zur semi-quantitativen Bestimmung der dopaminergen Neuronenzahl in der Rattensubantia nigra pars compacta vor.
Chapters in this video
0:04
Introduction
0:50
Confocal Microscopy and Image Acquisition
2:43
Image Analysis and Quantitation
4:33
Results: Quantitation of Dopaminergic Neuron Density in Brain Sections Using Automated Image Analysis
5:20
Conclusion
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