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Journal / Cancer Research / Rekonstruere humant retinoblastom in vitro
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Rekonstruere humant retinoblastom in vitro

Article DOI: 10.3791/62629-v • 06:52 min • October 11th, 2022
October 11th, 2022 •
1, 1
1Beijing Institute of Ophthalmology, Beijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing Ophthalmology & Visual Science Key Laboratory

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Vi beskriver en metode til generering af humant retinoblastom (RB) ved at introducere bialleliske RB1-mutationer i humane embryonale stamceller (hESC). RB-cellelinjer kunne også med succes dyrkes ved hjælp af den isolerede RB i en skål.

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