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Retinal Explant of the Adult Mouse Retina as an Ex Vivo Model for Studying Retinal Neurovascular Diseases
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JoVE Journal Medizin
Retinal Explant of the Adult Mouse Retina as an Ex Vivo Model for Studying Retinal Neurovascular Diseases

Retinal Explant of the Adult Mouse Retina as an Ex Vivo Model for Studying Retinal Neurovascular Diseases

DOI:
10.3791/63966-v

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06:51 min

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December 09, 2022

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, ,
1Eye Research Center and Department of Foundational Medical Studies,Oakland University William Beaumont School of Medicine, 2Eye Research Institute,Oakland University, 3Human Anatomy and Embryology Department, Mansoura Faculty of Medicine,Mansoura University

Kapitel

  • 00:02Introduction
  • 02:11Tissue Preparation
  • 02:45Tissue Dissection
  • 05:15Representative Results
  • 06:16Conclusion

Summary

Automatische Übersetzung

Automatische Übersetzung

This protocol presents and describes steps for the isolation, dissection, culturing, and staining of retinal explants obtained from an adult mouse. This method is beneficial as an ex vivo model for studying different retinal neurovascular diseases such as diabetic retinopathy.

Tags

Retinal ExplantEx Vivo ModelRetinal Neurovascular DiseasesRetinal NeuronsGlial CellsVascular CellsDiabetic RetinopathyRetinal DysfunctionMouse RetinaRetinal DissectionRetinal Culture

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