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Anestesia e Intubação de Filhotes de Camundongos Pré-Adolescentes para Cirurgia Cardiotorácica
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Anestesia e Intubação de Filhotes de Camundongos Pré-Adolescentes para Cirurgia Cardiotorácica

Article DOI: 10.3791/64004-v • 09:47 min • June 2nd, 2022
June 2nd, 2022 •
*1, 1,2, 3,4, 1,2, 1,2, *1,2
1Molecular Cardiology and Biophysics Division, Victor Chang Cardiac Research Institute, 2St Vincent’s Clinical School, University of New South Wales Sydney, 3Department of Anaesthesia, The Children’s Hospital at Westmead, 4School of Child and Adolescent Health, University of Sydney
* These authors contributed equally

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Modelos cirúrgicos cardiotorácicos em camundongos com >7 dias de idade requerem intubação, mas isso é um desafio para filhotes de camundongos pré-adolescentes (8-14 dias de idade) e há pouca informação sobre regimes anestésicos para intubação. Aqui, apresentamos esquemas posológicos de cetamina/xilazina/atropina em filhotes de camundongos C57BL/6J de 10 dias de idade que permitem a intubação endotraqueal, minimizando a mortalidade animal.

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Biologia Edição 184
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