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Journal / Immunology and Infection / 接触超敏反应作为过敏性接触性皮炎的小鼠模型…
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Immunology and Infection

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JoVE Journal Immunology and Infection
接触超敏反应作为过敏性接触性皮炎的小鼠模型
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接触超敏反应作为过敏性接触性皮炎的小鼠模型

Article DOI: 10.3791/64329-v • 08:25 min • September 26th, 2022
September 26th, 2022 •
1, 2, 1, 3
1Department of Clinical Immunology, Wroclaw Medical University, 2Department of Medical Physiology, Chair of Biomedical Sciences, Institute of Physiotherapy, Faculty of Health Sciences, Jagiellonian University Medical College, 3Chair of Biomedical Sciences, Faculty of Health Sciences, Jagiellonian University Medical College

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Summary
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接触性超敏反应（CHS）是过敏性接触性皮炎（ACD）的小鼠实验模型。CHS基于通过涂上胸部和腹部的剃须皮肤对反应性半抗原的致敏，随后用稀释的半抗原进行耳朵皮肤激发，引起肿胀反应，以各种方式评估。

Tags

免疫学和感染，第187期，小鼠模型，过敏性接触性皮炎（ACD），接触性超敏反应（CHS），耳肿胀，血管通透性，髓过氧化物酶（MPO），细胞因子，2，4，6-三硝基氯苯（TNCB），半抗原
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