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En kanin aortaklappestenose model induceret af direkte ballonskade

Article DOI: 10.3791/65078-v • 07:10 min • March 31st, 2023
March 31st, 2023 •
*1, *1, 1, 1, 1, 1, 1,2, 3, 1,4
1Cardiovascular Research Institute for Intractable Disease, College of Medicine, The Catholic University of Korea, 2Division of Cardiology, Incheon St. Mary’s Hospital, College of Medicine, The Catholic University of Korea, 3College of Pharmacy and Natural Medicine Research Institute, Mokpo National University, 4Division of Cardiology, Seoul St. Mary’s Hospital, College of Medicine, The Catholic University of Korea
* These authors contributed equally

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En passende dyremodel er nødvendig for at forstå de patologiske mekanismer, der ligger til grund for aortaklappestenose (AVS), og for at evaluere effekten af terapeutiske indgreb. Denne protokol beskriver en ny procedure til udvikling af AVS-kaninmodellen via en direkte ballonskade in vivo.

Tags

Kanin Aortaklappestenose Model Direkte ballonskade Dyremodeller Patologiske mekanismer AVS kaninmodeller Store dyreforsøg Kosttilskud Genmanipulation Eksperimentelle undersøgelser Protokol New Zealand hvide kaniner Kirurgisk procedure Postoperativ pleje Initiering Og progression Af AVS Patologiske mekanismer
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