Åsa Wallén-Mackenzie Department of Organismal Biology, Unit of Comparative Physiology Uppsala University Biography Publications Institution JoVE Articles Åsa Wallén-Mackenzie has not added a biography. If you are Åsa Wallén-Mackenzie and would like to personalize this page please email our Author Liaison for assistance. Publications Developmental Co-expression of Vglut2 and Nurr1 in a Mes-Di-Encephalic Continuum Preceeds Dopamine and Glutamate Neuron Specification Frontiers in Cell and Developmental Biology. 2019 | Pubmed ID: 31850343 Neurocircuitry of Reward and Addiction: Potential Impact of Dopamine-Glutamate Co-release As Future Target in Substance Use Disorder Journal of Clinical Medicine. Nov, 2019 | Pubmed ID: 31698743 Off-Target Effects in Transgenic Mice: Characterization of Dopamine Transporter (DAT)-Cre Transgenic Mouse Lines Exposes Multiple Non-Dopaminergic Neuronal Clusters Available for Selective Targeting Within Limbic Neurocircuitry ENeuro. Sep/Oct, 2019 | Pubmed ID: 31481399 The NeuroD6 Subtype of VTA Neurons Contributes to Psychostimulant Sensitization and Behavioral Reinforcement ENeuro. May/Jun, 2019 | Pubmed ID: 31097625 VGLUT2 Rs2290045 Genotype Moderates Environmental Sensitivity to Alcohol-related Problems in Three Samples of Youths European Child & Adolescent Psychiatry. Oct, 2019 | Pubmed ID: 30805764 Targeting VGLUT2 in Mature Dopamine Neurons Decreases Mesoaccumbal Glutamatergic Transmission and Identifies a Role for Glutamate Co-release in Synaptic Plasticity by Increasing Baseline AMPA/NMDA Ratio Frontiers in Neural Circuits. 2018 | Pubmed ID: 30210305 Validated Multi-step Approach for In vivo Recording and Analysis of Optogenetically Evoked Glutamate in the Mouse Globus Pallidus Journal of Neurochemistry. 04, 2018 | Pubmed ID: 29292502 Disrupting Glutamate Co-transmission Does Not Affect Acquisition of Conditioned Behavior Reinforced by Dopamine Neuron Activation Cell Reports. 03, 2017 | Pubmed ID: 28297663 Ethanol Affects Limbic and Striatal Presynaptic Glutamatergic and DNA Methylation Gene Expression in Outbred Rats Exposed to Early-life Stress Addiction Biology. Mar, 2017 | Pubmed ID: 26610727 Midbrain Gene Screening Identifies a New Mesoaccumbal Glutamatergic Pathway and a Marker for Dopamine Cells Neuroprotected in Parkinson's Disease Scientific Reports. 10, 2016 | Pubmed ID: 27762319 Reduced Gene Expression Levels Throughout the Mouse Subthalamic Nucleus Cause Cell Loss and Structural Disorganization Followed by Increased Motor Activity and Decreased Sugar Consumption ENeuro. Sep-Oct, 2016 | Pubmed ID: 27699212 In Situ Proximity Ligation Assay (PLA) Methods in Molecular Biology (Clifton, N.J.). 2015 | Pubmed ID: 26160573 Cre-driven Optogenetics in the Heterogeneous Genetic Panorama of the VTA Trends in Neurosciences. Jun, 2015 | Pubmed ID: 25962754 Targeted Deletion of Vglut2 Expression in the Embryonal Telencephalon Promotes an Anxiolytic Phenotype of the Adult Mouse Upsala Journal of Medical Sciences. 2015 | Pubmed ID: 25857802 Reply to Konsolaki and Skaliora: Habituation, Hyperlocomotion, and "genuine Hyperlocomotion" Proceedings of the National Academy of Sciences of the United States of America. Jan, 2015 | Pubmed ID: 25540419 SLC10A4 is a Vesicular Amine-associated Transporter Modulating Dopamine Homeostasis Biological Psychiatry. Mar, 2015 | Pubmed ID: 25176177 Increased Hippocampal Excitability and Impaired Spatial Memory Function in Mice Lacking VGLUT2 Selectively in Neurons Defined by Tyrosine Hydroxylase Promoter Activity Brain Structure & Function. Jul, 2015 | Pubmed ID: 24802380 Reduced Gene Expression Levels of Munc13-1 and Additional Components of the Presynaptic Exocytosis Machinery Upon Conditional Targeting of Vglut2 in the Adolescent Mouse Synapse (New York, N.Y.). Dec, 2014 | Pubmed ID: 25139798 The Multilingual Nature of Dopamine Neurons Progress in Brain Research. 2014 | Pubmed ID: 24968779 Haplotype-tag Single Nucleotide Polymorphism Analysis of the Vesicular Glutamate Transporter (VGLUT) Genes in Severely Alcoholic Women Psychiatry Research. Oct, 2014 | Pubmed ID: 24953423 Age- and Sex-dependence of Dopamine Release and Capacity for Recovery Identified in the Dorsal Striatum of C57/Bl6J Mice PloS One. 2014 | Pubmed ID: 24925086 Limiting Glutamate Transmission in a Vglut2-expressing Subpopulation of the Subthalamic Nucleus is Sufficient to Cause Hyperlocomotion Proceedings of the National Academy of Sciences of the United States of America. May, 2014 | Pubmed ID: 24821804 Glutamate Corelease Promotes Growth and Survival of Midbrain Dopamine Neurons The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2012 | Pubmed ID: 23197738 Enhanced Sucrose and Cocaine Self-administration and Cue-induced Drug Seeking After Loss of VGLUT2 in Midbrain Dopamine Neurons in Mice The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Aug, 2011 | Pubmed ID: 21880920 A Sensory Subpopulation Depends on Vesicular Glutamate Transporter 2 for Mechanical Pain, and Together with Substance P, Inflammatory Pain Proceedings of the National Academy of Sciences of the United States of America. Apr, 2011 | Pubmed ID: 21415372 VGLUT2-dependent Sensory Neurons in the TRPV1 Population Regulate Pain and Itch Neuron. Nov, 2010 | Pubmed ID: 21040852 Genetic Inactivation of the Vesicular Glutamate Transporter 2 (VGLUT2) in the Mouse: What Have We Learnt About Functional Glutamatergic Neurotransmission? Upsala Journal of Medical Sciences. Feb, 2010 | Pubmed ID: 20187846 VGLUT2 in Dopamine Neurons is Required for Psychostimulant-induced Behavioral Activation Proceedings of the National Academy of Sciences of the United States of America. Jan, 2010 | Pubmed ID: 20018672 Reduced VGLUT2 Expression Increases Motor Neuron Viability in Sod1(G93A) Mice Neurobiology of Disease. Jan, 2010 | Pubmed ID: 19770042 Restricted Cortical and Amygdaloid Removal of Vesicular Glutamate Transporter 2 in Preadolescent Mice Impacts Dopaminergic Activity and Neuronal Circuitry of Higher Brain Function The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Feb, 2009 | Pubmed ID: 19228977 Role of Glutamate in Locomotor Rhythm Generating Neuronal Circuitry Journal of Physiology, Paris. Nov-Dec, 2006 | Pubmed ID: 17618093 Vesicular Glutamate Transporter 2 is Required for Central Respiratory Rhythm Generation but Not for Locomotor Central Pattern Generation The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2006 | Pubmed ID: 17122055 Two Different Real-Time Place Preference Paradigms Using Optogenetics within the Ventral Tegmental Area of the Mouse Zisis Bimpisidis1, Niclas König1, Åsa Wallén-Mackenzie1 1Department of Organismal Biology, Unit of Comparative Physiology, Uppsala University JoVE 60867 Comportamiento
Two Different Real-Time Place Preference Paradigms Using Optogenetics within the Ventral Tegmental Area of the Mouse Zisis Bimpisidis1, Niclas König1, Åsa Wallén-Mackenzie1 1Department of Organismal Biology, Unit of Comparative Physiology, Uppsala University JoVE 60867 Comportamiento