Eiji Shigetomi Department of Neuropharmacology, Faculty of Medicine University of Yamanashi Biography Publications Institution JoVE Articles Eiji Shigetomi has not added a biography. If you are Eiji Shigetomi and would like to personalize this page please email our Author Liaison for assistance. Publications Transient Astrocytic MGluR5 Expression Drives Synaptic Plasticity and Subsequent Chronic Pain in Mice The Journal of Experimental Medicine. 04, 2022 | Pubmed ID: 35319723 Effects of Fatty Acid Metabolites on Nocturia Scientific Reports. 02, 2022 | Pubmed ID: 35197540 Abnormal Ca Signals in Reactive Astrocytes As a Common Cause of Brain Diseases International Journal of Molecular Sciences. Dec, 2021 | Pubmed ID: 35008573 Adenosine A Receptor Down-regulates Metabotropic Glutamate Receptor 5 in Astrocytes During Postnatal Development Glia. 11, 2021 | Pubmed ID: 34339538 Transnasal Transplantation of Human Induced Pluripotent Stem Cell-derived Microglia to the Brain of Immunocompetent Mice Glia. 10, 2021 | Pubmed ID: 34309082 Different Effects of GsMTx4 on Nocturia Associated with the Circadian Clock and Piezo1 Expression in Mice Life Sciences. Aug, 2021 | Pubmed ID: 33930366 Reactive Astrocyte-driven Epileptogenesis is Induced by Microglia Initially Activated Following Status Epilepticus JCI Insight. 05, 2021 | Pubmed ID: 33830944 Author Correction: Intermittent Restraint Stress Induces Circadian Misalignment in the Mouse Bladder, Leading to Nocturia Scientific Reports. Nov, 2019 | Pubmed ID: 31700120 Intermittent Restraint Stress Induces Circadian Misalignment in the Mouse Bladder, Leading to Nocturia Scientific Reports. 07, 2019 | Pubmed ID: 31296902 Aberrant Calcium Signals in Reactive Astrocytes: A Key Process in Neurological Disorders International Journal of Molecular Sciences. Feb, 2019 | Pubmed ID: 30823575 The Time-dependent Variation of ATP Release in Mouse Primary-cultured Urothelial Cells is Regulated by the Clock Gene Neurourology and Urodynamics. 11, 2018 | Pubmed ID: 30106187 Anti-Depressant Fluoxetine Reveals Its Therapeutic Effect Via Astrocytes EBioMedicine. Jun, 2018 | Pubmed ID: 29887330 The Oscillation of Intracellular Ca Influx Associated with the Circadian Expression of Piezo1 and TRPV4 in the Bladder Urothelium Scientific Reports. 04, 2018 | Pubmed ID: 29632308 Aberrant Astrocyte Ca Signals "AxCa Signals" Exacerbate Pathological Alterations in an Alexander Disease Model Glia. 05, 2018 | Pubmed ID: 29383757 Role of Purinergic Receptor P2Y1 in Spatiotemporal Ca Dynamics in Astrocytes The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. 02, 2018 | Pubmed ID: 29305530 The Circadian Expression of Piezo1, TRPV4, Connexin26, and VNUT, Associated with the Expression Levels of the Clock Genes in Mouse Primary Cultured Urothelial Cells Neurourology and Urodynamics. 03, 2018 | Pubmed ID: 28881406 Author Correction: Reactive Astrocytes Function As Phagocytes After Brain Ischemia Via ABCA1-mediated Pathway Nature Communications. 11, 2017 | Pubmed ID: 29138397 Neural Circuit-Specialized Astrocytes: Transcriptomic, Proteomic, Morphological, and Functional Evidence Neuron. Aug, 2017 | Pubmed ID: 28712653 Reactive Astrocytes Function As Phagocytes After Brain Ischemia Via ABCA1-mediated Pathway Nature Communications. 06, 2017 | Pubmed ID: 28642575 Transformation of Astrocytes to a Neuroprotective Phenotype by Microglia Via P2Y Receptor Downregulation Cell Reports. 05, 2017 | Pubmed ID: 28494865 P2Y-deficiency Increases Micturition Frequency and Attenuates Sustained Contractility of the Urinary Bladder in Mice Scientific Reports. 04, 2017 | Pubmed ID: 28396595 Clock Genes Regulate the Circadian Expression of Piezo1, TRPV4, Connexin26, and VNUT in an Ex Vivo Mouse Bladder Mucosa PloS One. 2017 | Pubmed ID: 28060940 The Clock Mutant Mouse is a Novel Experimental Model for Nocturia and Nocturnal Polyuria Neurourology and Urodynamics. Apr, 2017 | Pubmed ID: 27348079 Urothelial ATP Exocytosis: Regulation of Bladder Compliance in the Urine Storage Phase Scientific Reports. 07, 2016 | Pubmed ID: 27412485 Cortical Astrocytes Rewire Somatosensory Cortical Circuits for Peripheral Neuropathic Pain The Journal of Clinical Investigation. May, 2016 | Pubmed ID: 27064281 Probing the Complexities of Astrocyte Calcium Signaling Trends in Cell Biology. Apr, 2016 | Pubmed ID: 26896246 Müller Cell-mediated Neurite Outgrowth of the Retinal Ganglion Cells Via P2Y Receptor Signals Journal of Neurochemistry. Feb, 2016 | Pubmed ID: 26560804 Imaging Microdomains Calcio All'interno Di Territori Astrocita Intera Ed Endfeet Con GCaMPs Espresso Utilizzando Virus Adeno-associati The Journal of General Physiology. May, 2013 | Pubmed ID: 23589582 TRPA1 Canali Regolano Astrocita Riposo Sinapsi Inibitorie Efficacia Attraverso GAT-3 E Calcio Nature Neuroscience. Jan, 2012 | Pubmed ID: 22158513 Neuronali P2X2 Recettori Sono Sensori Mobili Di ATP Che Esplorano La Membrana Del Plasma Quando Attivato The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Nov, 2011 | Pubmed ID: 22090499 [Regolamento Synaptic Da Astrociti] Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. Oct, 2011 | Pubmed ID: 21986065 Caricamento Bulk Di Calcio Indicatore Coloranti Per Studiare Fisiologia Astrocita: Principali Limitazioni E Miglioramenti Utilizzando Mappe Morfologiche The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2011 | Pubmed ID: 21697385 Monitoraggio Astrocita Calcio Microdomains Con Membrana Migliorata Mirati Ai Giornalisti GCaMP Neuron Glia Biology. Dec, 2010 | Pubmed ID: 21205365 Un Sensore Ottico Geneticamente Mirato a Monitorare I Segnali Di Calcio Nei Processi Di Astrociti Nature Neuroscience. Jun, 2010 | Pubmed ID: 20495558 Due Forme Di Eccitabilità Calcio Astrocita Hanno Effetti Distinti Su NMDA Receptor Mediated Slow Inward Correnti Nei Neuroni Piramidali The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Jun, 2008 | Pubmed ID: 18579739 Rilevamento Trasmettitore-gated P2X Cazione Canale Attivazione in Vitro E in Vivo Nature Methods. Jan, 2008 | Pubmed ID: 18084300 [Complesso Normativo Purinergic Nelle Sinapsi Cerebrali] Nihon Shinkei Seishin Yakurigaku Zasshi = Japanese Journal of Psychopharmacology. Jun, 2007 | Pubmed ID: 17633523 Facilitazione Del Rilascio Di Glicina Spontanea Da Anossia Potenzia Recettore NMDA Corrente Nei Neuroni Hypoglossal Motore Del Ratto The European Journal of Neuroscience. Mar, 2007 | Pubmed ID: 17408431 Blocco Resistente Presinaptiche Voltaggio-dipendenti Ca2 + Canali Sottostanti Glutammato Release in Topi Nucleo Tractus Solitarii Brain Research. Aug, 2006 | Pubmed ID: 16814754 Un Dual-ruolo Interpretato Da ATP Extracellulare in Frequenza-filtraggio Della Rete Nucleo Tractus Solitarii Advances in Experimental Medicine and Biology. 2004 | Pubmed ID: 15602957 Potenziale D'azione Indipendente Rilascio Di Glutammato Da Ca2 + Voce Attraverso I Recettori P2X Presinaptico Induce Postsinaptica Infornamento Nella Rete Autonomica Del Tronco Encefalico The Journal of Neuroscience : the Official Journal of the Society for Neuroscience. Mar, 2004 | Pubmed ID: 15044552 ATP E Adenosina-mediata Segnalazione Nel Sistema Nervoso Centrale: Purinoceptors Sinaptica: La Fase Trifosfato Di Adenosina Svolgere Il Suo "doppio-ruolo" Journal of Pharmacological Sciences. Feb, 2004 | Pubmed ID: 14978346 Differenziale Aumenta Nei Livelli Del Recettore P2X in Vagale Neuroni Efferenti Ratto Seguendo Una Sezione Del Nervo Vagale Brain Research. Jul, 2003 | Pubmed ID: 12788520 Analisi Dei Meccanismi Molecolari Di Controllo Trasmissione Sinaptica Patch-clamp Registrazione Nelle Fette Del Tronco Encefalico Nihon Yakurigaku Zasshi. Folia Pharmacologica Japonica. Apr, 2003 | Pubmed ID: 12777844 In vivo Imaging del calcio a campo largo e a due fotoni da un topo utilizzando una grande finestra cranica Satoshi Manita1, Eiji Shigetomi2,3, Haruhiko Bito4, Schuichi Koizumi2,3, Kazuo Kitamura1 1Department of Neurophysiology, Faculty of Medicine, University of Yamanashi, 2Department of Neuropharmacology, Faculty of Medicine, University of Yamanashi, 3Yamanashi GLIA center, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 4Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo JoVE 64224 Neurociencia Trapianto di microglia derivata da cellule staminali pluripotenti indotte umane nel cervello di topi immunocompetenti tramite via transnasale non invasiva Bijay Parajuli1,2, Youichi Shinozaki1,2, Eiji Shigetomi1,2, Schuichi Koizumi1,2 1Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 2GLIA Center, University of Yamanashi JoVE 63574 Neurociencia Misura Vicino membrana plasmatica e Global Dynamics calcio intracellulare negli astrociti Eiji Shigetomi1, Baljit S. Khakh1 1Departments of Physiology and Neurobiology, David Geffen School of Medicine, University of California, Los Angeles JoVE 1142 Biología
In vivo Imaging del calcio a campo largo e a due fotoni da un topo utilizzando una grande finestra cranica Satoshi Manita1, Eiji Shigetomi2,3, Haruhiko Bito4, Schuichi Koizumi2,3, Kazuo Kitamura1 1Department of Neurophysiology, Faculty of Medicine, University of Yamanashi, 2Department of Neuropharmacology, Faculty of Medicine, University of Yamanashi, 3Yamanashi GLIA center, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 4Department of Neurochemistry, Graduate School of Medicine, The University of Tokyo JoVE 64224 Neurociencia
Trapianto di microglia derivata da cellule staminali pluripotenti indotte umane nel cervello di topi immunocompetenti tramite via transnasale non invasiva Bijay Parajuli1,2, Youichi Shinozaki1,2, Eiji Shigetomi1,2, Schuichi Koizumi1,2 1Department of Neuropharmacology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, 2GLIA Center, University of Yamanashi JoVE 63574 Neurociencia
Misura Vicino membrana plasmatica e Global Dynamics calcio intracellulare negli astrociti Eiji Shigetomi1, Baljit S. Khakh1 1Departments of Physiology and Neurobiology, David Geffen School of Medicine, University of California, Los Angeles JoVE 1142 Biología