Jordan J. Green Biomedical Engineering, Translational Tissue Engineering Center, Institute for Nanobiotechnology, Ophthalmology, Oncology, Neurosurgery, Materials Science and Engineering, Chemical and Biomolecular Engineering, and the Bloomberg-Kimmel Institute for Cancer Immunotherapy Johns Hopkins University School of Medicine Biography Publications Institution JoVE Articles Jordan J. Green has not added a biography. If you are Jordan J. Green and would like to personalize this page please email our Author Liaison for assistance. Publications Non-Viral Delivery To Enable Genome Editing Trends in Biotechnology. Sep, 2018 | Pubmed ID: 30278987 Bioreducible Polymeric Nanoparticles Containing Multiplexed Cancer Stem Cell Regulating MiRNAs Inhibit Glioblastoma Growth and Prolong Survival Nano Letters. Jul, 2018 | Pubmed ID: 29927251 Bacterial TRNase-Based Gene Therapy with Poly(β-Amino Ester) Nanoparticles for Suppressing Melanoma Tumor Growth and Relapse Advanced Healthcare Materials. Aug, 2018 | Pubmed ID: 29888531 Injectable Drug Depot Engineered to Release Multiple Ophthalmic Therapeutic Agents with Precise Time Profiles for Postoperative Treatment Following Ocular Surgery Acta Biomaterialia. Jun, 2018 | Pubmed ID: 29684622 Anisotropic Biodegradable Lipid Coated Particles for Spatially Dynamic Protein Presentation Acta Biomaterialia. May, 2018 | Pubmed ID: 29631048 Biodegradable Polymeric Nanoparticles for Therapeutic Cancer Treatments Annual Review of Chemical and Biomolecular Engineering. Jun, 2018 | Pubmed ID: 29579402 Nanoscale Artificial Antigen Presenting Cells for Cancer Immunotherapy Molecular Immunology. Jun, 2018 | Pubmed ID: 29525074 Biomimetic Peptide Display from a Polymeric Nanoparticle Surface for Targeting and Antitumor Activity to Human Triple-negative Breast Cancer Cells Journal of Biomedical Materials Research. Part A. Jun, 2018 | Pubmed ID: 29424479 Biodegradable STING Agonist Nanoparticles for Enhanced Cancer Immunotherapy Nanomedicine : Nanotechnology, Biology, and Medicine. 02, 2018 | Pubmed ID: 29127039 Therapeutic Potential of an Anti-angiogenic Multimodal Biomimetic Peptide in Hepatocellular Carcinoma Oncotarget. Nov, 2017 | Pubmed ID: 29254183 Surface Engineering for Lymphocyte Programming Advanced Drug Delivery Reviews. May, 2017 | Pubmed ID: 28501510 A Triple-Fluorophore-Labeled Nucleic Acid PH Nanosensor to Investigate Non-viral Gene Delivery Molecular Therapy : the Journal of the American Society of Gene Therapy. 07, 2017 | Pubmed ID: 28479046 Polymeric Nanoparticles As Cancer-specific DNA Delivery Vectors to Human Hepatocellular Carcinoma Journal of Controlled Release : Official Journal of the Controlled Release Society. Oct, 2017 | Pubmed ID: 28351668 Nanoparticle Tracking Analysis for Determination of Hydrodynamic Diameter, Concentration, and Zeta-Potential of Polyplex Nanoparticles Methods in Molecular Biology (Clifton, N.J.). 2017 | Pubmed ID: 28238128 Continuous Microfluidic Assembly of Biodegradable Poly(beta-amino Ester)/DNA Nanoparticles for Enhanced Gene Delivery Journal of Biomedical Materials Research. Part A. 06, 2017 | Pubmed ID: 28177587 Tyrosine Kinase Blocking Collagen IV-derived Peptide Suppresses Ocular Neovascularization and Vascular Leakage Science Translational Medicine. 01, 2017 | Pubmed ID: 28100839 Noninvasive Targeted Transcranial Neuromodulation Via Focused Ultrasound Gated Drug Release from Nanoemulsions Nano Letters. 02, 2017 | Pubmed ID: 28094959 Gene Delivery Nanoparticles to Modulate Angiogenesis Advanced Drug Delivery Reviews. Sep, 2017 | Pubmed ID: 27913120 Polymeric Nanoparticle-based Delivery of TRAIL DNA for Cancer-specific Killing Bioengineering & Translational Medicine. Jun, 2016 | Pubmed ID: 28349127 Mimicking Biological Functionality with Polymers for Biomedical Applications Nature. 12, 2016 | Pubmed ID: 27974772 Synthesis and Application of Poly(ethylene Glycol)-co-poly(β-amino Ester) Copolymers for Small Cell Lung Cancer Gene Therapy Acta Biomaterialia. 09, 2016 | Pubmed ID: 27262740 Non-viral Nucleic Acid Containing Nanoparticles As Cancer Therapeutics Expert Opinion on Drug Delivery. Oct, 2016 | Pubmed ID: 27248202 Non-virally Engineered Human Adipose Mesenchymal Stem Cells Produce BMP4, Target Brain Tumors, and Extend Survival Biomaterials. 09, 2016 | Pubmed ID: 27240162 Highlights of Children with Cancer UK's Workshop on Drug Delivery in Paediatric Brain Tumours Ecancermedicalscience. 2016 | Pubmed ID: 27110286 Quantification of Cellular and Nuclear Uptake Rates of Polymeric Gene Delivery Nanoparticles and DNA Plasmids Via Flow Cytometry Acta Biomaterialia. 06, 2016 | Pubmed ID: 27019146 Nanoparticle-mediated Transcriptional Modification Enhances Neuronal Differentiation of Human Neural Stem Cells Following Transplantation in Rat Brain Biomaterials. Apr, 2016 | Pubmed ID: 26828681 Layer-by-layer Inorganic/polymeric Nanoparticles for Kinetically Controlled Multigene Delivery Journal of Biomedical Materials Research. Part A. 03, 2016 | Pubmed ID: 26519869 Bioreducible Poly(Beta-Amino Ester)s for Intracellular Delivery of SiRNA Methods in Molecular Biology (Clifton, N.J.). 2016 | Pubmed ID: 26472444 Shaping the Future of Nanomedicine: Anisotropy in Polymeric Nanoparticle Design Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. Mar-Apr, 2016 | Pubmed ID: 25981390 Biodegradable Polymer Iron Oxide Nanocomposites: the Future of Biocompatible Magnetism Nanomedicine (London, England). 2015 | Pubmed ID: 26608843 Exploring the Role of Polymer Structure on Intracellular Nucleic Acid Delivery Via Polymeric Nanoparticles Journal of Controlled Release : Official Journal of the Controlled Release Society. Dec, 2015 | Pubmed ID: 26433125 Gene Delivery Polymer Structure-function Relationships Elucidated Via Principal Component Analysis Chemical Communications (Cambridge, England). Aug, 2015 | Pubmed ID: 26126593 Targeted Polymeric Nanoparticles for Cancer Gene Therapy Journal of Drug Targeting. 2015 | Pubmed ID: 26061296 Platelet-Derived Growth Factor BB Enhances Osteogenesis of Adipose-Derived But Not Bone Marrow-Derived Mesenchymal Stromal/Stem Cells Stem Cells (Dayton, Ohio). Sep, 2015 | Pubmed ID: 26013357 Polymeric Nanoparticles for Nonviral Gene Therapy Extend Brain Tumor Survival in Vivo ACS Nano. Feb, 2015 | Pubmed ID: 25643235 An Automated Multidimensional Thin Film Stretching Device for the Generation of Anisotropic Polymeric Micro- and Nanoparticles Journal of Biomedical Materials Research. Part A. Aug, 2015 | Pubmed ID: 25641799 Degradable Polymer-coated Gold Nanoparticles for Co-delivery of DNA and SiRNA Acta Biomaterialia. Jan, 2015 | Pubmed ID: 25246314 Highlights from the Latest Articles in Nanomedicine Nanomedicine (London, England). 05, 2014 | Pubmed ID: 24978461 Hypoxia-inducible Factors and RAB22A Mediate Formation of Microvesicles That Stimulate Breast Cancer Invasion and Metastasis Proceedings of the National Academy of Sciences of the United States of America. Aug, 2014 | Pubmed ID: 24938788 Biodegradable Polymeric Nanoparticles Show High Efficacy and Specificity at DNA Delivery to Human Glioblastoma in Vitro and in Vivo ACS Nano. May, 2014 | Pubmed ID: 24766032 Bioreducible Cationic Polymer-based Nanoparticles for Efficient and Environmentally Triggered Cytoplasmic SiRNA Delivery to Primary Human Brain Cancer Cells ACS Nano. Apr, 2014 | Pubmed ID: 24673565 Differential Polymer Structure Tunes Mechanism of Cellular Uptake and Transfection Routes of Poly(β-amino Ester) Polyplexes in Human Breast Cancer Cells Bioconjugate Chemistry. Jan, 2014 | Pubmed ID: 24320687 Biomolecule Delivery to Engineer the Cellular Microenvironment for Regenerative Medicine Annals of Biomedical Engineering. Jul, 2014 | Pubmed ID: 24170072 Particle Shape Dependence of CD8+ T Cell Activation by Artificial Antigen Presenting Cells Biomaterials. Jan, 2014 | Pubmed ID: 24099710 Evaluating the Potential of Poly(beta-amino Ester) Nanoparticles for Reprogramming Human Fibroblasts to Become Induced Pluripotent Stem Cells International Journal of Nanomedicine. 2013 | Pubmed ID: 24348039 Independent Vs. Cooperative Binding in Polyethylenimine-DNA and Poly(L-lysine)-DNA Polyplexes The Journal of Physical Chemistry. B. Aug, 2013 | Pubmed ID: 23941196 Long-term Suppression of Ocular Neovascularization by Intraocular Injection of Biodegradable Polymeric Particles Containing a Serpin-derived Peptide Biomaterials. Oct, 2013 | Pubmed ID: 23849876 Nanoengineering Approaches to the Design of Artificial Antigen-presenting Cells Nanomedicine (London, England). Jul, 2013 | Pubmed ID: 23837856 Bioengineered Nanoparticles for SiRNA Delivery Wiley Interdisciplinary Reviews. Nanomedicine and Nanobiotechnology. Sep-Oct, 2013 | Pubmed ID: 23821336 (3-aminopropyl)-4-methylpiperazine End-capped Poly(1,4-butanediol Diacrylate-co-4-amino-1-butanol)-based Multilayer Films for Gene Delivery ACS Applied Materials & Interfaces. Jul, 2013 | Pubmed ID: 23755861 A Bioreducible Linear Poly(β-amino Ester) for SiRNA Delivery Chemical Communications (Cambridge, England). Jun, 2013 | Pubmed ID: 23646347 The Effect and Role of Carbon Atoms in Poly(β-amino Ester)s for DNA Binding and Gene Delivery Journal of the American Chemical Society. May, 2013 | Pubmed ID: 23570657 Student Award Winner in the Ph.D. Category for the 2013 Society for Biomaterials Annual Meeting and Exposition, April 10-13, 2013, Boston, Massachusetts : Biomaterial-mediated Cancer-specific DNA Delivery to Liver Cell Cultures Using Synthetic Poly(beta-amino Ester)s Journal of Biomedical Materials Research. Part A. Jul, 2013 | Pubmed ID: 23559534 Poly(beta-aminoester) 纳米粒子-传递的 P53 具有对小细胞肺癌患者体外和体内活性。 Molecular Cancer Therapeutics. Jan, 2013 | Pubmed ID: 23364678 SiRNA 纳米药物: Bioreducible 材料的承诺。 Expert Review of Medical Devices. Jan, 2013 | Pubmed ID: 23278217 高分子结构与退化机制使高度有效纳米 SiRNA 和 DNA 传递到人类的脑肿瘤发生微妙变化。 Advanced Healthcare Materials. Sep, 2012 | Pubmed ID: 23184674 吸收和聚合物纳米粒转染是依赖于聚合物结束组结构,但很大程度上独立于纳米粒子物理和化学特性。 Molecular Pharmaceutics. Nov, 2012 | Pubmed ID: 22970908 半胱胺终止聚 (β-氨基酯) S SiRNA 交付给人骨髓间充质干细胞和成骨分化的增强。 Biomaterials. Nov, 2012 | Pubmed ID: 22871421 Poly(β-amino Ester)-纳米粒子介导的基因转染的视网膜色素上皮细胞在体外和体内。 PloS One. 2012 | Pubmed ID: 22629417 2011 丽塔沙弗讲座: 纳米颗粒细胞内核酸交货。 Annals of Biomedical Engineering. Jul, 2012 | Pubmed ID: 22451256 治疗性血管生成使用基因工程内皮细胞。 Journal of Controlled Release : Official Journal of the Controlled Release Society. Jun, 2012 | Pubmed ID: 22450331 基因传递纳米粒子特定人体微血管和 Macrovasculature。 Nanomedicine : Nanotechnology, Biology, and Medicine. Oct, 2012 | Pubmed ID: 22306159 新型检测方法量化的质粒封装聚合物纳米粒子的数目。 Small (Weinheim an Der Bergstrasse, Germany). Feb, 2012 | Pubmed ID: 22139973 聚合物和无机载体传递非病毒核酸的研究进展。 Therapeutic Delivery. Apr, 2011 | Pubmed ID: 22826857 合成聚 (酯胺) 和聚 (酰胺基胺) 高效 DNA 和 SiRNA 交付给人血管内皮细胞的纳米粒子。 International Journal of Nanomedicine. 2011 | Pubmed ID: 22228998 基聚合物疏水性和端基改性聚合物基因转染对影响。 Biomacromolecules. Oct, 2011 | Pubmed ID: 21888340 Poly(β-amino Ester)-DNA 复合物的: 时间分辨荧光和细胞基因转染的研究。 Journal of Controlled Release : Official Journal of the Controlled Release Society. Sep, 2011 | Pubmed ID: 21699928 非病毒基因传递纳米粒子基于聚 (β-氨基酯) 的胶质母细胞瘤的治疗。 Biomaterials. Aug, 2011 | Pubmed ID: 21536325 治疗性血管生成及抗血管生成的药物传递战略。 Expert Opinion on Drug Delivery. Apr, 2011 | Pubmed ID: 21338327 终端的功能化与分子量的乳腺上皮 2 D 文化和三维器官文化基因传递聚合物和转染效果之间的关系。 Biomaterials. Nov, 2010 | Pubmed ID: 20674001 静电的表面修饰提高基因传递。 Expert Opinion on Drug Delivery. Apr, 2010 | Pubmed ID: 20201712 通过纳米涂层的组织特异性基因传递。 Biomaterials. Feb, 2010 | Pubmed ID: 19850333 使用可生物降解聚合物纳米粒子增强血管生成人类干细胞的基因工程。 Proceedings of the National Academy of Sciences of the United States of America. Feb, 2010 | Pubmed ID: 19805054 Small-Molecule End-Groups of Linear Polymer Determine Cell-type Gene-Delivery Efficacy Advanced Materials (Deerfield Beach, Fla.). Dec, 2009 | Pubmed ID: 25165411 可降解聚合物基因载体。 Conference Proceedings : ... Annual International Conference of the IEEE Engineering in Medicine and Biology Society. IEEE Engineering in Medicine and Biology Society. Conference. 2009 | Pubmed ID: 19964958 纳米粒子传递自杀基因疗法有效地减少了对小鼠卵巢肿瘤负担。 Cancer Research. Aug, 2009 | Pubmed ID: 19643734 小干扰 RNA 传递的金,聚 (β-氨基酯) 纳米粒子。 Nano Letters. Jun, 2009 | Pubmed ID: 19422265 聚 (β-氨基酯): 合成和基因的传递程序。 Methods in Molecular Biology (Clifton, N.J.). 2009 | Pubmed ID: 19085119 白喉毒素 DNA 纳米粒子交付有效杀死 Mesothelin 表达胰腺癌细胞。 Cancer Biology & Therapy. Oct, 2008 | Pubmed ID: 19039293 纳米粒的基因转移到人类胚胎干细胞的殖民地。 Nano Letters. Oct, 2008 | Pubmed ID: 18754690 组合聚合物库方法生成的非病毒基因载体的洞察。 Accounts of Chemical Research. May, 2008 | Pubmed ID: 18507402 静电配体涂层的纳米粒子使配体特异性基因传递到主细胞。 Nano Letters. Apr, 2007 | Pubmed ID: 17362046 可生物降解聚合物载体在人血管内皮细胞基因转染。 Bioconjugate Chemistry. Sep-Oct, 2006 | Pubmed ID: 16984124 CD8+ T 细胞活化的各向异性聚合物人工抗原呈现细胞的制备 Elana Ben-Akiva*1, Kelly R. Rhodes*1, Randall A. Meyer1, Jordan J. Green2 1Biomedical Engineering, Translational Tissue Engineering Center, Institute for Nanobiotechnology, Johns Hopkins University School of Medicine, 2Biomedical Engineering, Translational Tissue Engineering Center, Institute for Nanobiotechnology, Ophthalmology, Oncology, Neurosurgery, Materials Science and Engineering, Chemical and Biomolecular Engineering, and the Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine JoVE 58332 Medio ambiente 高分子基因传递纳米粒子的纳米粒子跟踪分析和高通量流式细胞仪评价 Ron B. Shmueli1,2, Nupura S. Bhise1,2, Jordan J. Green1,2,3,4 1Biomedical Engineering Department, Johns Hopkins University School of Medicine, 2Translational Tissue Engineering Center, Johns Hopkins University School of Medicine, 3Wilmer Eye Institute, Johns Hopkins University School of Medicine, 4Institute for Nanobiotechnology, Johns Hopkins University School of Medicine JoVE 50176 Bioingeniería
CD8+ T 细胞活化的各向异性聚合物人工抗原呈现细胞的制备 Elana Ben-Akiva*1, Kelly R. Rhodes*1, Randall A. Meyer1, Jordan J. Green2 1Biomedical Engineering, Translational Tissue Engineering Center, Institute for Nanobiotechnology, Johns Hopkins University School of Medicine, 2Biomedical Engineering, Translational Tissue Engineering Center, Institute for Nanobiotechnology, Ophthalmology, Oncology, Neurosurgery, Materials Science and Engineering, Chemical and Biomolecular Engineering, and the Bloomberg-Kimmel Institute for Cancer Immunotherapy, Johns Hopkins University School of Medicine JoVE 58332 Medio ambiente
高分子基因传递纳米粒子的纳米粒子跟踪分析和高通量流式细胞仪评价 Ron B. Shmueli1,2, Nupura S. Bhise1,2, Jordan J. Green1,2,3,4 1Biomedical Engineering Department, Johns Hopkins University School of Medicine, 2Translational Tissue Engineering Center, Johns Hopkins University School of Medicine, 3Wilmer Eye Institute, Johns Hopkins University School of Medicine, 4Institute for Nanobiotechnology, Johns Hopkins University School of Medicine JoVE 50176 Bioingeniería