Lena Serghides Toronto General Research Institute University Health Network Biography Publications Institution JoVE Articles Lena Serghides has not added a biography. If you are Lena Serghides and would like to personalize this page please email our Author Liaison for assistance. Publications Chronic HIV Infection Impairs Nonopsonic Phagocytosis of Malaria Parasites Journal of Acquired Immune Deficiency Syndromes (1999). Feb, 2015 | Pubmed ID: 25415293 HIV Protease Inhibitor Use During Pregnancy is Associated with Decreased Progesterone Levels, Suggesting a Potential Mechanism Contributing to Fetal Growth Restriction The Journal of Infectious Diseases. Jan, 2015 | Pubmed ID: 25030058 PPARγ Agonists Improve Survival and Neurocognitive Outcomes in Experimental Cerebral Malaria and Induce Neuroprotective Pathways in Human Malaria PLoS Pathogens. Mar, 2014 | Pubmed ID: 24603727 Murine Plasmodium Chabaudi Malaria Increases Mucosal Immune Activation and the Expression of Putative HIV Susceptibility Markers in the Gut and Genital Mucosae Journal of Acquired Immune Deficiency Syndromes (1999). Apr, 2014 | Pubmed ID: 24256632 The Importance of Motherhood in HIV-positive Women of Reproductive Age in Ontario, Canada AIDS Care. 2014 | Pubmed ID: 24206065 Functional Roles for C5a and C5aR but Not C5L2 in the Pathogenesis of Human and Experimental Cerebral Malaria Infection and Immunity. Jan, 2014 | Pubmed ID: 24191300 HIV Infection Deregulates Tim-3 Expression on Innate Cells: Combination Antiretroviral Therapy Results in Partial Restoration Journal of Acquired Immune Deficiency Syndromes (1999). Jun, 2013 | Pubmed ID: 23314411 HIV Infection Deregulates Innate Immunity to Malaria Despite Combination Antiretroviral Therapy AIDS (London, England). Jan, 2013 | Pubmed ID: 23291537 A Phase I Clinical Study of Inhaled Nitric Oxide in Healthy Adults Journal of Cystic Fibrosis : Official Journal of the European Cystic Fibrosis Society. Jul, 2012 | Pubmed ID: 22520076 The Case for the Use of PPARγ Agonists As an Adjunctive Therapy for Cerebral Malaria PPAR Research. 2012 | Pubmed ID: 21772838 Inhaled Nitric Oxide Reduces Endothelial Activation and Parasite Accumulation in the Brain, and Enhances Survival in Experimental Cerebral Malaria PloS One. 2011 | Pubmed ID: 22110737 Nitric Oxide for the Adjunctive Treatment of Severe Malaria: Hypothesis and Rationale Medical Hypotheses. Sep, 2011 | Pubmed ID: 21745716 Caspase-12 Dampens the Immune Response to Malaria Independently of the Inflammasome by Targeting NF-kappaB Signaling Journal of Immunology (Baltimore, Md. : 1950). Nov, 2010 | Pubmed ID: 20876354 Cerebral Malaria: Human Versus Mouse Studies Trends in Parasitology. Jun, 2010 | Pubmed ID: 20382077 Use of Peroxisome Proliferator-activated Receptor Gamma Agonists As Adjunctive Treatment for Plasmodium Falciparum Malaria: a Randomized, Double-blind, Placebo-controlled Trial Clinical Infectious Diseases : an Official Publication of the Infectious Diseases Society of America. Sep, 2009 | Pubmed ID: 19673614 Rosiglitazone Modulates the Innate Immune Response to Plasmodium Falciparum Infection and Improves Outcome in Experimental Cerebral Malaria The Journal of Infectious Diseases. May, 2009 | Pubmed ID: 19392627 C5a Enhances Dysregulated Inflammatory and Angiogenic Responses to Malaria in Vitro: Potential Implications for Placental Malaria PloS One. 2009 | Pubmed ID: 19308263 C5 Deficiency and C5a or C5aR Blockade Protects Against Cerebral Malaria The Journal of Experimental Medicine. May, 2008 | Pubmed ID: 18426986 Pyruvate Kinase Deficiency and Malaria The New England Journal of Medicine. Apr, 2008 | Pubmed ID: 18420493 HIV Impairs Opsonic Phagocytic Clearance of Pregnancy-associated Malaria Parasites PLoS Medicine. May, 2007 | Pubmed ID: 17535103 Disruption of CD36 Impairs Cytokine Response to Plasmodium Falciparum Glycosylphosphatidylinositol and Confers Susceptibility to Severe and Fatal Malaria in Vivo Journal of Immunology (Baltimore, Md. : 1950). Mar, 2007 | Pubmed ID: 17339496 Disruption of JNK2 Decreases the Cytokine Response to Plasmodium Falciparum Glycosylphosphatidylinositol in Vitro and Confers Protection in a Cerebral Malaria Model Journal of Immunology (Baltimore, Md. : 1950). Nov, 2006 | Pubmed ID: 17056565 Approaches to Studying Costimulation of Human Antiviral T Cell Responses: Prospects for Immunotherapeutic Vaccines Immunologic Research. 2006 | Pubmed ID: 17003516 Placental Chondroitin Sulfate A-binding Malarial Isolates Evade Innate Phagocytic Clearance The Journal of Infectious Diseases. Jul, 2006 | Pubmed ID: 16741892 Evaluation of OX40 Ligand As a Costimulator of Human Antiviral Memory CD8 T Cell Responses: Comparison with B7.1 and 4-1BBL Journal of Immunology (Baltimore, Md. : 1950). Nov, 2005 | Pubmed ID: 16272289 Nonopsonic Phagocytosis of Erythrocytes Infected with Ring-stage Plasmodium Falciparum Infection and Immunity. Apr, 2005 | Pubmed ID: 15784606 Peroxisome Proliferator-activated Receptor Gamma and Retinoid X Receptor Agonists Have Minimal Effects on the Interaction of Endothelial Cells with Plasmodium Falciparum-infected Erythrocytes Infection and Immunity. Feb, 2005 | Pubmed ID: 15664966 CD36 Mediates the Phagocytosis of Plasmodium Falciparum-infected Erythrocytes by Rodent Macrophages The Journal of Infectious Diseases. Jan, 2004 | Pubmed ID: 14722884 Effect of HIV-1 Antiretroviral Drugs on Cytoadherence and Phagocytic Clearance of Plasmodium Falciparum-parasitised Erythrocytes Lancet (London, England). Sep, 2003 | Pubmed ID: 14522535 CD36 and Malaria: Friends or Foes? Trends in Parasitology. Oct, 2003 | Pubmed ID: 14519584 CD36-mediated Nonopsonic Phagocytosis of Erythrocytes Infected with Stage I and IIA Gametocytes of Plasmodium Falciparum Infection and Immunity. Jan, 2003 | Pubmed ID: 12496189 Innate Immunity to Malaria Caused by Plasmodium Falciparum Clinical and Investigative Medicine. Médecine Clinique Et Experimentale. Dec, 2002 | Pubmed ID: 12516999 Mechanism of Protection Induced by Vitamin A in Falciparum Malaria Lancet (London, England). Apr, 2002 | Pubmed ID: 11978340 CD36 Deficiency Induced by Antiretroviral Therapy AIDS (London, England). Feb, 2002 | Pubmed ID: 11834946 En Constance Finney1, Lena Serghides2 1Department of Biological Sciences, University of Calgary, 2Toronto General Research Institute, University Health Network Inmunología e infección
En Constance Finney1, Lena Serghides2 1Department of Biological Sciences, University of Calgary, 2Toronto General Research Institute, University Health Network Inmunología e infección